Fabrication and Formation Mechanism of Electrospun Spatially Defined Fibrous Patterning Structures on Conductive and Insulating Substrates

Abstract:

Besides the conductive patterning substrate, spatially well-defined microfibrous architectures can also be electrospun by using an insulating topographically structured collector (e.g. a nylon fabric). In both cases, it is proposed that the formation of the electrospun microfibrous patterns can be ascribed to the re-distribution of static electric field whenever collectors with different topography are introduced. Moreover, a series of simulation of the static electric field for various collectors (e.g. flat Al foil, conductive and insulating patterned substrates) have been systematically made to illustrate the formation mechanism, respectively. Our results are considered to warrant further scientific understanding on the formation of electrospun microfibrous patterning constructs, and helpful for easy generation of spatially defined architectures which have applications in a variety of areas such as tissue engineering, cell adhesion, proliferation and migration, etc.

• Periodical: Key Engineering Materials (Volumes 609-610)
• Pages: 842-848
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.609-610.842
• Online since: April 2014
• Authors: Shu Liang Liu, Guang Hui Sun, Yuan Yuan Huang, Bin Sun, Hong Di Zhang, Yun-Ze Long*
• Keywords: Electro-Spinning, Microfibrous Patterns, Static Electric Field

References

[1] D.H. Reneker, and A.L. Yarin, Polymer [J], 2008, 49(10): 2387-2425.

[2] J. Zheng, Y.Z. Long, B. Sun, Z.H. Zhang, F. Shao, H.D. Zhang, Z.M. Zhang, and J.Y. Huang, Chin Phys B[J], 2012, 21(4): 048102/1-6.

[3] B. Sun, Y. Z. Long, H. D. Zhang, M. M. Li, J. L. Duvail, X. Y. Jiang, and H. L. Yin, Prog Poly Sci [J], 2013, Doi: 10. 1016/j. progpolymsci. 2013. 06. 002.

[4] B. Sun, Y.Z. Long, S.L. Liu,  Y.Y. Huang,  J. Ma,  H.D. Zhang,  G.Z. Shen and  S. Xu, Nanoscale [J], 2013, DOI: 10. 1039/C3NR01832F.

[5] W. Cui, Y. Zhou, and J. Chang, Sci Technol Adv Mater [J], 2010, 11: 014108/1-11.

[6] A. Greiner, and J.H. Wendorff, Adv Polym Sci [J], 2008, 219: 107-171.

[7] J.D. Schiffman, and C.L. Schauer, Polymer Rev [J], 2008, 48(2): 317-352.

[8] Z.M. Huang, Y.Z. Zhang, M. Kotaki, and S. Ramakrishna, Compos Sci Technol [J], 2003, 63: 2223-2253.

[9] D. Li, Y.L. Wang, and Y.N. Xia, Nano Lett [J], 2003, 3(8): 1167-1171.

[10] Y.Q. Wu, L.A. Carnell, and R.L. Clark, Polymer [J], 2007, 48(19): 5653-5661.

[11] J.S. Tan, Y.Z. Long, and M.M. Li, Chin Phys Lett [J], 2008, 25(8): 3067-3070.

[12] M.M. Li, Y.Z. Long, D.Y. Yang, J.S. Sun, H.X. Yin, Z.L. Zhao, W.H. Kong, X.Y. Jiang, and Z.Y. Fan, J Mater Chem [J], 2011, 21: 13159-13162.

[13] S.G. Kumbar, R. James, S.P. Nukavarapu, and C.T. Laurencin, Biomed Mater [J], 2008, 3(3): 034002/1-15.

[14] X. Zong, H. Bien, C.Y. Chung, L. Yin, D. Fang, B.S. Hsiao, B. Chu, and E. Entcheva, Biomaterials [J], 2005, 26: 5330-5338.

DOI: 10.1016/j.biomaterials.2005.01.052

[15] W. Li, C.T. Laurencin, E.J. Caterson, R.S. Tuan, and F.K. Ko, J Biomed Mater Res [J], 2002, 60: 613-621.

[16] W.J. Li, K.G. Danielson, P.G. Alexander, and R.S. Tuan, J Biomed Mater Res A [J], 2003, 67: 1105-1114.

[17] Z.W. Ma, M. Kotaki, R. Inai, and S. Ramakrishna, Tissue Eng [J], 2005, 11: 101-109.

[18] W.J. Li, R. Tuli, C. Okafor, A. Derfoul, K.G. Danielson, D.J. Hall, and R.S. Tuan, Biomaterials [J], 2005, 26: 599-609.

DOI: 10.1016/j.biomaterials.2004.03.005

[19] C.A. Bonino, K.E. menko, S.I. Jeong, M.D. Krebs, E. Alsberg, and S.A. Khan, Small [J], 2012, 8(12): 1928-(1936).

[20] N. Bhattarai, Z.S. Li, D. Edmondson, and M. Q. Zhang, Adv Mater [J], 2006, 18: 1463-1467.

[21] R.S. Barhate, and S. Ramakrishna, J Membr Sci [J], 2007, 296: 1-8.

[22] K. Zhang, X.F. Wang, D.Z. Jing, Y. Yang, and M.F. Zhu, Biomed Mater [J], 2009, 4: 035004/1-6.

[23] D.M. Zhang, and J. Chang, Adv Mater [J], 2007, 19: 3664-3667.

[24] Z.W. Ding, A. Salim, and B. Ziaie, Langmuir [J], 2009, 25(17): 9648-9652.

[25] J. Lannutti, D. Reneker, T. Ma, D. Tomasko, and D. Farson, Mater Sci Eng C [J], 2007, 27: 504-509.

DOI: 10.1016/j.msec.2006.05.019

[26] Y.Z. Wang, G.X. Wang, L. Chen, H. Li, T.Y. Yin, B.C. Wang, J. C-M Lee, and Q.S. Yu, Biofabrication [J], 2009, 1: 015001/1-9.

[27] X.G. Zhou, Q. Cai, N. Yan, X.L. Deng, and X.P. Yang, J Biomed Mater Res A [J], 2010, 95A(3): 755-765.

[28] S.J. Cho, B. Kim, T. An, and G. Lim, Langmuir [J], 2010, 26(18): 14395-14399.

[29] Y.Q. Wu, Z.X. Dong, S. Wilson, and R.L. Clark, Polymer [J], 2010, 51: 3244-3248.

[30] C. Vaquette, and J.J. Cooper-White, Acta Biomater [J], 2011, 7: 2544-2557.

[31] D. Li, G. Ouyang, J. T. McCann, and Y.N. Xia, Nano Lett [J], 2005, 5(5): 913-916.

[32] B. Sun, Y.Z. Long, F. Yu, M.M. Li, H.D. Zhang, W.J. Li, and T.X. Xu, Nanoscale [J], 2012, 4(6): 2134-2137.