Sintering Behavior of Nanostructured Hydroxyapatite Ceramics

Abstract:

The synthesis of nanoparticles appropriate for the preparation of nanostructured hydroxyapatite ceramics intended for bone repairs and regeneration is an interesting field of biomaterials research today. In this work nanoparticles of hydroxyapatite were obtained by the precipitation method using conventional magnetic stirring (A) and ultra turrex homogenizer (T1) accompanied with surfactant (T2) and dispersant agents (T3). In all cases, powders with nanometric dimensions were obtained and the unique calcium phosphate phase detected was hydroxyapatite (HAp). The powders sintering behaviour was studied. The ceramics obtained from powders prepared by magnetic stirring (A) showed the best values of final density (96.7 %) which it was in agreement with the lowest temperature of the beginning of shrinking (648.6 °C) during sintering determined by dilatometry. Nanostructured nature of these ceramics was confirmed by Scanning Electron Microscopy (SEM).

• Periodical: Key Engineering Materials (Volume 631)
• Pages: 207-211
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.631.207
• Online since: November 2014
• Authors: José A. Delgado*, Lizette Morejón Alonso, Juliana Nacimento, Karla P. Macedo, Alexandre Antunes, Marize Varella, Adrian Alfonso, Salvador Martínez, Maite García-Vallès
• Keywords: Hydroxyapatite (HA), Nanoparticle, Nanostructured Ceramics, Sintering Behavior

References

[1] M. Eriksson, Y. Liu, J. Hu, L. Gao, M. Nygren, Z. Shen, Transparent hydroxyapatite ceramics with nanograin structure prepared by high pressure spark plasma sintering at the minimized sintering temperature, J Eur Ceram Soc 31 (2011) 1533–40.

DOI: 10.1016/j.jeurceramsoc.2011.03.021

[2] S. Bose, S. Dasgupta, S. Tarafder, A. Bandyopadhyay, Microwave-processed nanocrystalline hydroxyapatite: simultaneous enhancement of mechanical and biological properties, Acta Biomater 6 (2010) 3782–90.

DOI: 10.1016/j.actbio.2010.03.016

[3] Y. Cai, Y. Liu, W. Yan, Q. Hu, J. Tao, M. Zhang, Role of hydroxyapatite nanoparticle size in bone cell proliferation, J Mater Chem 17 (2007) 3780–7.

DOI: 10.1039/b705129h

[4] J. Zhan, Y.H. Tseng, J.C.C. Chan, C.Y. Mou, Biomimetic formation of hydroxyapatite nanorods by a single-crystal-to-single-crystal transformation, Adv Funct Mater 15 (2005) 2005–10.

DOI: 10.1002/adfm.200500274

[5] A. Paz, D. Guadarrama, M. Lopez, J.E. Gonzalez, N. Brizuela, J. Aragon, A comparative study of hydroxyapatite nanoparticles synthesized by different routes, Quim Nova 35 (2012) 1724–7.

DOI: 10.1590/s0100-40422012000900004

[6] R. Murugan, S. Ramakrishna, Development of nanocomposites for bone grafting, Composites Science and Technology 65 (2005) 2385–2406.

DOI: 10.1016/j.compscitech.2005.07.022