Paper Titles

Preface, Committees, Sponsors

Value Added Bioceramics: A Review of the Developments and Progress in India
p.3

Transformation of Apatite Cement to B-Type Carbonate Apatite Using Different Atmosphere
p.9

Nanocrystalline Apatites: A Versatile Functionalizable Platform for Biomedical Applications for Bone Engineering… and beyond
p.14

Osteoconductivity and Bioresorption of an Interconnecting Porous Carbonate Apatite with Enhanced Mechanical Strength
p.23

Regulation of DCPD Formation on β-TCP Granular Surface by Exposing Different Concentration of Acidic Calcium Phosphate Solution
p.27

Analysis on the Setting of Brushite Bone Cement after Storage in the Humid Environment
p.32

Conversion of Marine Structures to Calcium Phosphate Materials: Mechanisms of Conversion Using Two Different Phosphate Solutions
p.36

Fabrication of Bone-Like Apatite-Phosphatidylcholine Composite Thin Film by Biomimetic Method
p.40

HomeKey Engineering MaterialsKey Engineering Materials Vol. 696Nanocrystalline Apatites: A Versatile...

Nanocrystalline Apatites: A Versatile Functionalizable Platform for Biomedical Applications for Bone Engineering… and beyond

Article Preview

Abstract:

This contribution gathers various examples illustrating the fact that nanocrystalline apatites represent a genuine multi-functionalizable platform for a wide range of biomedical applications. It is indeed possible to convey additional functionalities to the already appealing properties of biomimetic apatites, via appropriate ionic substitutions and/or through controlled molecular adsorptions. In link with bone regeneration, we depict here examples of enhanced osteoconduction/induction and of the addition of antibacterial features to bone implants. But we also point out the promise of apatite-based colloidal nanoparticles in other domains not related to bone, such as nanomedicine (cell diagnosis/therapy), which we address by conferring luminescence properties and by adding cell recognition abilities.

You might also be interested in these eBooks

Bioceramics 27

Info:

Periodical:

Key Engineering Materials (Volume 696)

Pages:

14-22

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.696.14

Citation:

Cite this paper

Online since:

May 2016

Authors:

Christophe Drouet*, Christian Rey, Christèle Combes, Sophie Cazalbou, Stephanie Sarda, David Grossin

Keywords:

Adsorption, Apatite, Biomimetism, Bone Engineering, Cell Diagnostic, Cell Therapy, Ion Exchange, Multifunctionality

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

© 2016 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

* - Corresponding Author

[1] D.O. Wagner, P. Aspenberg. Where did bone come from?, Acta Orthopaedica 82 (2011) 393-398.

DOI: 10.3109/17453674.2011.588861

[2] J.P. Bonjour. Calcium and Phosphate: A Duet of Ions Playing for Bone Health, Journal of the American College of Nutrition 30 (2011) 438S-448S.

DOI: 10.1080/07315724.2011.10719988

[3] F.C.M. Driessens, J.W.E. Vandijk, R.M.H. Verbeeck. THE ROLE OF BONE-MINERAL IN CALCIUM AND PHOSPHATE HOMEOSTASIS, Bulletin Des Societes Chimiques Belges 95 (1986) 337-342.

DOI: 10.1002/bscb.19860950508

[4] R.Z. LeGeros. Calcium Phosphate-Based Osteoinductive Materials, Chemical Reviews 108 (2008) 4742-4753.

DOI: 10.1021/cr800427g

[5] Q.L. Luo, J.D. Andrade. Cooperative adsorption of proteins onto hydroxyapatite, Journal of Colloid and Interface Science 200 (1998) 104-113.

DOI: 10.1006/jcis.1997.5364

[6] S. Cazalbou, C. Combes, D. Eichert, C. Rey, M.J. Glimcher. Poorly crystalline apatites: evolution and maturation in vitro and in vivo, Journal of Bone and Mineral Metabolism 22 (2004) 310-317.

DOI: 10.1007/s00774-004-0488-0

[7] D. Eichert, H. Sfihi, C. Combes, C. Rey. Specific characteristics of wet nanocrystalline apatites. Consequences on biomaterials and bone tissue, Bioceramics, Vol 16 254-2 (2004) 927-930.

DOI: 10.4028/www.scientific.net/kem.254-256.927

[8] C. Rey, J. Lian, M. Grynpas, F. Shapiro, L. Zylberberg, M.J. Glimcher. Non-apatitic environments in bone mineral: FT-IR detection, biological properties and changes in several disease states, Connective tissue research 21 (1989) 267-273.

DOI: 10.3109/03008208909050016

[9] N. Vandecandelaere, C. Rey, C. Drouet. Biomimetic apatite-based biomaterials: on the critical impact of synthesis and post-synthesis parameters, Journal of Materials Science-Materials in Medicine 23 (2012) 2593-2606.

DOI: 10.1007/s10856-012-4719-y

[10] C. Drouet, M. -T. Carayon, C. Combes, C. Rey. Surface enrichment of biomimetic apatites with biologically-active ions Mg2+ and Sr2+: A preamble to the activation of bone repair materials, Materials Science and Engineering C 28 (2008) 1544-1550.

DOI: 10.1016/j.msec.2008.04.011

[11] C. Drouet, J. Gomez-Morales, M. Iafisco, S. Sarda. Calcium phosphate surface tailoring technologies for drug delivering and tissue engineering. in: Rimondini L, Bianchi CL, Vernè E, (Eds. ). Surface Tailoring of Inorganic Materials for Biomedical Applications L. Rimondini, C.L. Bianchi, E. Vernè. Bentham Science, e-book, 2012. pp.43-111.

DOI: 10.2174/978160805462611201010043

[12] L. Benaziz, A. Barroug, A. Legrouri, C. Rey, A. Lebugle. Adsorption of O-phospho-L-serine and L-serine onto poorly crystalline apatite, Journal of Colloid and Interface Science 238 (2001) 48-53.

DOI: 10.1006/jcis.2001.7450

[13] N. Bihi, M. Bennani-Ziatni, A. Taitai, A. Lebugle. Adsorption of aminoacids onto bone-like carbonated calcium phosphates, Annales De Chimie-Science Des Materiaux 27 (2002) 61-70.

DOI: 10.1016/s0151-9107(02)80033-2

[14] M. Choimet, A. Tourrette, C. Drouet. Adsorption of nucleotides on biomimetic apatite: The case of cytidine 5' monophosphate (CMP), Journal of Colloid and Interface Science 456 (2015) 132-137.

DOI: 10.1016/j.jcis.2015.06.021

[15] C. Combes, C. Rey. Adsorption of proteins and calcium phosphate materials bioactivity, Biomaterials 23 (2002) 2817-2823.

DOI: 10.1016/s0142-9612(02)00073-x

[16] A. Grunenwald, C. Keyser, A.M. Sautereau, E. Crubezy, B. Ludes, C. Drouet. Adsorption of DNA on biomimetic apatites: Toward the understanding of the role of bone and tooth mineral on the preservation of ancient DNA, Applied Surface Science 292 (2014).

DOI: 10.1016/j.apsusc.2013.12.063

[17] K. Hammami, H.E. Feki, O. Marsan, C. Drouet. Adsorption of nucleotides on biomimetic apatite: The case of adenosine 5' monophosphate (AMP), Applied Surface Science 353 (2015) 165-172.

DOI: 10.1016/j.apsusc.2015.06.068

[18] M. Iafisco, E. Varoni, M. Di Foggia, S. Pietronave, M. Fini, N. Roveri, L. Rimondini, M. Prat. Conjugation of hydroxyapatite nanocrystals with human immunoglobulin G for nanomedical applications, Colloids and Surfaces B-Biointerfaces 90 (2012).

DOI: 10.1016/j.colsurfb.2011.09.033

[19] V. Midy, C. Rey, E. Bres, M. Dard. Basic fibroblast growth factor adsorption and release properties of calcium phosphate, Journal of Biomedical Materials Research 41 (1998) 405-411.

DOI: 10.1002/(sici)1097-4636(19980905)41:3<405::aid-jbm10>3.0.co;2-h

[20] H. AUTEFAGE, F. BRIAND-MESANGE, S. CAZALBOU, C. DROUET, D. FOURMY, S. GONCALVES, J. SALLES, C. COMBES, P. SWIDER, C. REY. Adsorption and Release of BMP-2 on Nanocrystalline Apatite-Coated and Uncoated Hydroxyapatite/beta-Tricalcium Phosphate Porous Ceramics, JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS 91B (2009).

DOI: 10.1002/jbm.b.31447

[21] C.G. Weber, M. Mueller, N. Vandecandelaere, I. Trick, A. Burger-Kentischer, T. Maucher, C. Drouet. Enzyme-functionalized biomimetic apatites: concept and perspectives in view of innovative medical approaches, Journal of Materials Science-Materials in Medicine 25 (2014).

DOI: 10.1007/s10856-013-5097-9

[22] A. Barroug, M.J. Glimcher. Hydroxyapatite crystals as a local delivery system for cisplatin: adsorption and release of cisplatin in vitro, Journal of Orthopaedic Research 20 (2002) 274-280.

DOI: 10.1016/s0736-0266(01)00105-x

[23] R. Bosco, M. Iafisco, J. van den Beucken, S. Leeuwenburgh, J. Jansen. Adsorption of alendronate onto biomimetic apatite nanocrystals to develop drug carrier coating for bone implants, Bioceramics 24 529-530 (2013) 475-479.

DOI: 10.4028/www.scientific.net/kem.529-530.475

[24] S. Cazalbou, G. Bertrand, C. Drouet. Tetracycline-Loaded Biomimetic Apatite: An Adsorption Study, The Journal of Physical Chemistry B 119 (2015) 3014-3024.

DOI: 10.1021/jp5116756

[25] C.A.S. de Souza, A.P.V. Colombo, R.M. Souto, C.M. Silva-Boghossian, J.M. Granjeiro, G.G. Alves, A.M. Rossi, M.H.M. Rocha-Leao. Adsorption of chlorhexidine on synthetic hydroxyapatite and in vitro biological activity, Colloids and Surfaces B-Biointerfaces 87 (2011).

DOI: 10.1016/j.colsurfb.2011.05.035

[26] M. Iafisco, B. Palazzo, G. Martra, N. Margiotta, S. Piccinonna, G. Natile, V. Gandin, C. Marzano, N. Roveri. Nanocrystalline carbonate-apatites: role of Ca/P ratio on the upload and release of anticancer platinum bisphosphonates, Nanoscale 4 (2012).

DOI: 10.1039/c1nr11147g

[27] B. Palazzo, M. Iafisco, M. Laforgia, N. Margiotta, G. Natile, C.L. Bianchi, D. Walsh, S. Mann, N. Roveri. Biomimetic hydroxyapatite-drug nanocrystals as potential bone substitutes with antitumor drug delivery properties, Advanced Functional Materials 17 (2007).

DOI: 10.1002/adfm.200600361

[28] P. Pascaud, F. Errassifi, F. Brouillet, S. Sarda, A. Barroug, A. Legrouri, C. Rey. Adsorption on apatitic calcium phosphates for drug delivery: interaction with bisphosphonate molecules, Journal of Materials Science-Materials in Medicine 25 (2014).

DOI: 10.1007/s10856-014-5218-0

[29] C. Drouet. Apatite Formation: Why It May Not Work as Planned, and How to Conclusively Identify Apatite Compounds, Biomed Research International (2013) 12.

DOI: 10.1155/2013/490946

[30] H. Autefage. Ph.D. Thesis - Rôle ostéoinducteur d'un revêtement d'apatite carbonatée nanocristalline sur des céramiques de phosphate de calcium biphasique - INP Toulouse. 2009 (171 p. ).

[31] C. Drouet, J. Gómez-Morales, M. Iafisco, S. Sarda, Calcium Phosphate Surface Tailoring Technologies for Drug Delivering and Tissue Engineering and applied aspects, in: L. Rimondini, C. L. Bianchi and E. Vernè (Eds. ), Surface Tailoring of Inorganic Materials for Biomedical Applications. 2012, e-book, eISBN 978-1-60805-462-6, pp.43-111.

DOI: 10.2174/978160805462611201010043

[32] M. Iafisco, J. Manuel Delgado-Lopez, E.M. Varoni, A. Tampieri, L. Rimondini, J. Gomez-Morales, M. Prat. Cell Surface Receptor Targeted Biomimetic Apatite Nanocrystals for Cancer Therapy, Small 9 (2013) 3834-3844.

DOI: 10.1002/smll.201202843

[33] I. Rodriguez-Ruiz, J. Manuel Delgado-Lopez, M.A. Duran-Olivencia, M. Iafisco, A. Tampieri, D. Colangelo, M. Prat, J. Gomez-Morales. pH-Responsive Delivery of Doxorubicin from Citrate-Apatite Nanocrystals with Tailored Carbonate Content, Langmuir 29 (2013).

DOI: 10.1021/la4008334

[34] A. Al-Kattan, V. Santran, P. Dufour, J. Dexpert-Ghys, C. Drouet. Novel contributions on luminescent apatite-based colloids intended for medical imaging, Journal of Biomaterials Applications 28 (2014) 697-707.

DOI: 10.1177/0885328212473510

[35] A. BOULADJINE, A. AL-KATTAN, P. DUFOUR, C. DROUET. New Advances in Nanocrystalline Apatite Colloids Intended for Cellular Drug Delivery, LANGMUIR 25 (2009) 12256-12265.

DOI: 10.1021/la901671j

[36] D. C, Al-Kattan A, Choimet M, Tourrette A, Santran V, J. Dexpert-Ghys, B. Pipy, F. Brouillet, M. Tourbin. Biomimetic Apatite-Based Functional Nanoparticles as Promising Newcomers in Nanomedicine: Overview of 10 Years of Initiatory Research, HSOA Journal of General Practice and Medical Diagnosis (GPMD) 1 (2015).

DOI: 10.24966/imph-2493/100001

[37] A. Doat, M. Fanjul, F. Pelle, E. Hollande, A. Lebugle. Europium-doped bioapatite: a new photostable biological probe, internalizable by human cells, Biomaterials 24 (2003) 3365-3371.

DOI: 10.1016/s0142-9612(03)00169-8

[38] V.V. Sokolova, I. Radtke, R. Heumann, M. Epple. Effective transfection of cells with multi-shell calcium phosphate-DNA nanoparticles, Biomaterials 27 (2006) 3147-3153.

DOI: 10.1016/j.biomaterials.2005.12.030

[39] A. AL-KATTAN, P. DUFOUR, J. DEXPERT-GHYS, C. DROUET. Preparation and Physicochemical Characteristics of Luminescent Apatite-Based Colloids, JOURNAL OF PHYSICAL CHEMISTRY C 114 (2010) 2918-2924. Patent.

DOI: 10.1021/jp910923g

[40] H. AUTEFAGE, S. CAZALBOU, C. COMBES, C. REY. Porous biomaterials surface activation method, US patent n°12/487, 101 (2009).