Osteoconductivity and Bioresorption of an Interconnecting Porous Carbonate Apatite with Enhanced Mechanical Strength

Tram Nguyen Xuan Thanh; Michito Maruta; Kanji Tsuru; Shigeki Matsuya; Kunio Ishikawa

doi:10.4028/www.scientific.net/KEM.696.23

Paper Titles

Value Added Bioceramics: A Review of the Developments and Progress in India
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Transformation of Apatite Cement to B-Type Carbonate Apatite Using Different Atmosphere
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Nanocrystalline Apatites: A Versatile Functionalizable Platform for Biomedical Applications for Bone Engineering… and beyond
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Osteoconductivity and Bioresorption of an Interconnecting Porous Carbonate Apatite with Enhanced Mechanical Strength
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Regulation of DCPD Formation on β-TCP Granular Surface by Exposing Different Concentration of Acidic Calcium Phosphate Solution
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Analysis on the Setting of Brushite Bone Cement after Storage in the Humid Environment
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Conversion of Marine Structures to Calcium Phosphate Materials: Mechanisms of Conversion Using Two Different Phosphate Solutions
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Fabrication of Bone-Like Apatite-Phosphatidylcholine Composite Thin Film by Biomimetic Method
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HomeKey Engineering MaterialsKey Engineering Materials Vol. 696Osteoconductivity and Bioresorption of an...

Osteoconductivity and Bioresorption of an Interconnecting Porous Carbonate Apatite with Enhanced Mechanical Strength

Abstract:

We have established a processing method to fabricate three - dimensional porous carbonate apatite (CO₃Ap) with interconnected porous structure and improved mechanical strength. Briefly, porous CO₃Ap materials were produced via phosphorization of porous calcite precursor in hydrothermal condition. In order to make porous calcite precursor, negative replication of modified polyurethane foam template was conducted. In this study, an in vivo behavior of that porous CO₃Ap was evaluated. The interconnected porous CO₃Ap material was implanted in the tibia of Japanese male rabbits and removed after a period of 6 months. Micro-computed tomography (μ-CT) scanner and histological analysis were used to characterize the bone formation response of the porous CO₃Ap. The results suggest that porous CO₃Ap with enhanced mechanical strength was not only osteoconductive but also bioresorbable therefore it could be used as bone substitute material.

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Periodical:

Key Engineering Materials (Volume 696)

Pages:

23-26

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.696.23

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Online since:

May 2016

Authors:

Tram Nguyen Xuan Thanh, Michito Maruta, Kanji Tsuru, Shigeki Matsuya, Kunio Ishikawa

Keywords:

Bioresorption, Carbonate Apatite, Mechanical Strength, Osteoconductivity, Porous Material

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