Synthesis of Biodegradable β-TCP/PLGA Composites Using Microwave Energy

Abstract:

Biodegradable β-tricalcium phosphate (β-TCP)/poly (lactide-co-glycolide) (PLGA) composites were synthesized by in situ polymerization with microwave energy. The influence of the β-TCP content in β-TCP/PLGA composites on the molecular weight, crystallinity, microstructure, and mechanical properties was investigated. As the molecular weight of composites decreased, the β-TCP content increased up to 10 wt%, while further raising of the β-TCP content above 10%, the molecular weight increased with increasing β-TCP content. This behavior may be ascribed to the superheating effect or nonthermal effect induced by microwave energy. It was found that the bending strength and Young’s modulus of the β-TCP/PLGA composites were proportional to the molecular weight of PLGA. The bending strength of the β-TCP/PLGA composites ranged from 18 to 38 MPa, while Young’s modulus was in the range from 2 to 6 GPa.

• Periodical: Materials Science Forum (Volumes 510-511)
• Pages: 758-761
• DOI: https://doi.org/10.4028/www.scientific.net/MSF.510-511.758
• Online since: March 2006
• Authors: Hyeong Ho Jin, Sang Ho Min, Kyu Hong Hwang, Ik Min Park, Hong Chae Park, Seog Young Yoon
• Keywords: Biodegradable, Micro-Wave, PLGA, TCP

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