Preparation and Characterization of Chitosan-Based Scaffolds for Biomedical Applications
Porous chitosan/brushite composite scaffolds were prepared by a freeze-drying technique, starting from brushite suspensions in chitosan solutions. The obtained scaffolds showed a regular macroporous and interconnected structure with brushite particles uniformly distributed in the chitosan matrix. The variation of the brushite concentration affected the microstructure of the final freeze-dried scaffold, in particular, its porosity and its average pore size. The yield strengths of the composite scaffolds could also be improved by the increase of the brushite content.
Paula Maria Vilarinho
J. V. Araújo et al., "Preparation and Characterization of Chitosan-Based Scaffolds for Biomedical Applications ", Materials Science Forum, Vols. 514-516, pp. 1005-1009, 2006