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Preparation and Characterization of Chitosan-Based Scaffolds for Biomedical Applications

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Abstract:

Porous chitosan/brushite composite scaffolds were prepared by a freeze-drying technique, starting from brushite suspensions in chitosan solutions. The obtained scaffolds showed a regular macroporous and interconnected structure with brushite particles uniformly distributed in the chitosan matrix. The variation of the brushite concentration affected the microstructure of the final freeze-dried scaffold, in particular, its porosity and its average pore size. The yield strengths of the composite scaffolds could also be improved by the increase of the brushite content.

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Advanced Materials Forum III View Preview

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Periodical:

Materials Science Forum (Volumes 514-516)

Pages:

1005-1009

DOI:

https://doi.org/10.4028/www.scientific.net/MSF.514-516.1005

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Online since:

May 2006

Authors:

José V. Araújo, J.A. Lopes da Silva, Margarida M. Almeida, Maria Elisabete V. Costa

Keywords:

Biomaterial, Brushite, Calcium Phosphate, Chitosan (CS), Composite, Scaffold

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© 2006 Trans Tech Publications Ltd. All Rights Reserved

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