Physicochemical Characterization of Novel Chitosan-Soy Protein/ TEOS Porous Hybrids for Tissue Engineering Applications

S.S. Silva; J. Miguel Oliveira; João F. Mano; Rui L. Reis

doi:10.4028/www.scientific.net/MSF.514-516.1000

Paper Titles

Bone Tissue Engineering Constructs Based on Starch Scaffolds and Bone Marrow Cells Cultured in a Flow Perfusion Bioreactor
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Bioactive Composite Materials for Bone Tissue Applications
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Study of the Fosfosal Controlled Permeation through Glutaraldehyde Crosslinked Chitosan Membranes
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Enzymatic Degradation Behaviour of Starch Conjugated Phosphorylated Chitosan
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Physicochemical Characterization of Novel Chitosan-Soy Protein/ TEOS Porous Hybrids for Tissue Engineering Applications
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Preparation and Characterization of Chitosan-Based Scaffolds for Biomedical Applications
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Liquid Crystalline Behaviour of Chitosan in Formic, Acetic, Monochloroacetic Acid Solutions
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Synthesis of N-Carboxymethyl Chitosan Beads for Controlled Drug Delivery Applications
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Influence of Molecular Weight and Crystallinity of Poly(L-Lactic Acid) on the Adhesion and Proliferation of Human Osteoblast Like Cells
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HomeMaterials Science ForumMaterials Science Forum Vols. 514-516Physicochemical Characterization of Novel...

Physicochemical Characterization of Novel Chitosan-Soy Protein/ TEOS Porous Hybrids for Tissue Engineering Applications

Abstract:

In this paper we report a new type of cross-linked porous structure based on a chitosansoy protein blend system developed by means of combining a sol-gel process with the freeze-drying technique. The final structure was investigated by Fourier transform infrared spectroscopy with attenuated total reflectance (FTIR-ATR), contact angle measurements and the morphology by scanning electron microscopy (SEM). The water uptake capability and the weight loss were measured up to 14 days and their mechanical properties were assessed with compression tests. Results showed that the addition of tetraethyl orthosilicate (TEOS) to the chitosan-soy protein blend system provide specific interactions at the interface between the two polymers allowing to tailor the size and distribution as well as the degradation rate of the hybrids. Finally, TEOS incorporation induces an increase of the surface energy that influences the final physicochemical properties of the materials.

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Periodical:

Materials Science Forum (Volumes 514-516)

Pages:

1000-1004

DOI:

https://doi.org/10.4028/www.scientific.net/MSF.514-516.1000

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Online since:

May 2006

Authors:

S.S. Silva, J. Miguel Oliveira, João F. Mano, Rui L. Reis

Keywords:

Biodegradable, Chitosan (CS), Scaffold, Sol-Gel (SG), Soy Protein, TEOS, Tissue Engineering of Cartilage

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