Human Platelet Extracts Stimulate the Terminative Differentiation of Growth-Plate Chondrocytes in Rabbit

Abstract:

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Objective:To observe the effect of human platelet extracts on proliferation and differentiation of rabbit growth-plate chondrocytes in monolayer and fabrication of tissue engineering cartilage in vitro. Method: To determine the effects of platelet extracts at different concentrations on proliferation and differentiation of rabbit growth-plate chondrocytes using 3H-TdR、PNP and HE staining. Results: Platelet extracts had very strong stimulative effects on proliferation and differentiation of chondrocytes, especially the hypertropization (termination) of chondrocytes.

Info:

Periodical:

Materials Science Forum (Volumes 610-613)

Main Theme:

Edited by:

Zhong Wei Gu, Yafang Han, Fu Sheng Pan, Xitao Wang, Duan Weng and Shaoxiong Zhou

Pages:

1070-1075

DOI:

10.4028/www.scientific.net/MSF.610-613.1070

Citation:

L. Yu et al., "Human Platelet Extracts Stimulate the Terminative Differentiation of Growth-Plate Chondrocytes in Rabbit", Materials Science Forum, Vols. 610-613, pp. 1070-1075, 2009

Online since:

January 2009

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Price:

$35.00

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