Study on Biomineralization of Poly (Vinyl Alcohol) Film via a Biomimetic Process
Organic polymer–hydroxyapatite (HA) hybrid was expected as a promising bone substitute. In this work, poly(vinyl alcohol) (PVA) was used as a polymer substrate and the PVA-HA hybrid was prepared by a biomimetic process. The resultant PVA-HA composites were characterized by Fourier transform infrared spectroscopy, X-ray diffraction, thermogravimetric analysis and scanning electron microscopy. It was found that HA could deposite on PVA surface when PVA soaked in water for a little swelling and then was carried out CaP treatment previously. The formed HA showed bone-like structure and had a good interaction with PVA substrate. The resultant hybrid might exhibit good osteoconductivity and biocompatibility, and could be expected as a useful scaffold for bone tissue regeneration.
Zhong Wei Gu, Yafang Han, Fu Sheng Pan, Xitao Wang, Duan Weng and Shaoxiong Zhou
Y. W. Guo et al., "Study on Biomineralization of Poly (Vinyl Alcohol) Film via a Biomimetic Process ", Materials Science Forum, Vols. 610-613, pp. 1090-1095, 2009