Designing Nano-Hydroxyapatite in the Polyelectrolyte Complex Macroporous Scaffold Based on Chitosan and Hyaluronic Acid

Jing Di Chen; Ying Jun Wang; Xiao Feng Chen

doi:10.4028/www.scientific.net/MSF.610-613.1252

Paper Titles

Preparation and Characteristics of Gradient Silk Fibroin/Hydroxyapatite Porous Composites
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Study on Preparation and Properties of Nitric Oxide Releasing Polyurethane
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Effects of Exercise on Antitumor Efficacy of DHAQ-Loaded PLA-PLL-RGD Nanoparticles in Hepatocellular Carcinoma
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Flexibility Modification of Konjac Glucomannan Film by Deacetylation
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Designing Nano-Hydroxyapatite in the Polyelectrolyte Complex Macroporous Scaffold Based on Chitosan and Hyaluronic Acid
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Exothermal Behavior during the Hydration of the PCCP+DCPA System Cement
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Surface Modification of Chitosan Membranes by Oxygen Plasma Treatment
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Effect of Si Content on the Synthesis of Ti₃SiC₂ Bulk Material by Pressureless Sintering
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Surface Hydrophilicity Improvement of RGP Contact Lens Material by Oxygen Plasma Treatment
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HomeMaterials Science ForumMaterials Science Forum Vols. 610-613Designing Nano-Hydroxyapatite in the...

Designing Nano-Hydroxyapatite in the Polyelectrolyte Complex Macroporous Scaffold Based on Chitosan and Hyaluronic Acid

Abstract:

Owing to the unique characters of the hybrid scaffold components, a novel biodegradable porous composite scaffold was prepared. The nano hydroxyapatite (HAP) (73~136 nm) was crystallized in situ on the organic polyelectrolyte complex matrix through a biomimetic method. The polyelectrolyte complex composed of chitosan and hyaluronic acid had strong impacts on the formation of the nano HAP and directed in situ crystallization of the nano HAP as template. The in situ nano HAP reduced the interfacial energy and presented nano intensifier to the nano hybrid scaffold. Meanwhile, the scaffold kept high porosity.