Obtaining Tetracalcium Pohosphate and Hydroxyapatite in Powder Form by Wet Method

Abstract:

The development of research in the area of advanced materials and tissue engineering has increased greatly in recent years found that bioceramics are outstanding in the replacement and regeneration of bone tissue, mainly formed by the calcium phosphate ceramics. The objective of this research is to obtain the calcium phosphate where Ca/P = 1.67 and 2.0, to observe the formation of phases after having subjected these materials to heat treatment. The calcium phosphate was produced by the wet method using a direct reaction of neutralization and characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and X-ray microanalysis (EDS). The XRD results confirm the presence of hydroxyapatite phase in the sample with Ca/P = 1.67, where as the phosphates prepared with Ca/P = 2.0 ratio show a combination of hydroxyapatite and phase β- tricalcium phosphate. The micrographs obtained are characteristic of ceramic material called calcium phosphate. EDS confirmed the presence of Ca, P and O in the material.

• Periodical: Materials Science Forum (Volumes 660-661)
• Pages: 954-958
• DOI: https://doi.org/10.4028/www.scientific.net/MSF.660-661.954
• Online since: October 2010
• Authors: Sara Verusca de Oliveira, Marcus Vinícius Lia Fook, Elaine Patrícia Araújo, Keila Machado Medeiros, Guilherme Portela Rabello, Renata Barbosa, Edcleide Maria Araújo
• Keywords: Calcium Phosphate, Hydroxyapatite (HAP), Tetracalcium Phosphate (TTCP), X-Ray Diffraction (XRD)

References

[1] S.J. Román and R. Reis in: Biodegradable systems in medica functions: desing, processing, testing and applications. (1º ed Edtied CRC: Boca Ratón, 2004).

[2] A. Helebrant, L. Jonásofá and L. Sanda: Ceram-Silikáty Vol. 46, (2002), p.9.

[3] K.S. Katti: Biointerfaces Vol. 37 (17) (2004), p.133.

[4] S.V. Oliveira, M.V.L. Fook, E.P. Araújo, A.C.B.M. Fook, R.S.C. Lima and W.P.F. Barbosa: Comparasion of calcium CPP, Hap and TeCP phosphates, Obtained by Direct (Trans Tech Publications, 2009).

DOI: 10.4028/www.scientific.net/kem.396-398.557

[5] J.C. Elliot: Struture and chemistry of the apatites and other calcium orthophosphates. (Amsterdam Elsevier, 389 1994).

[6] M. Bohner: Calcium orthophosphates in medicine: from ceramics to calcium phosphate cements. Injury Vol. 31, (2000), p.37.

DOI: 10.1016/s0020-1383(00)80022-4

[7] R.Z. Legeros: Calcium phosphate in oral biology and medicine. (San Francisco, Meyers, 98 1991).