Synthesis, Microstructure and Properties of Poly(L-Lactic Acid-Co-α-Alanine) Obtained by Direct Melting Copolymerization
A new poly(ester amide)s (PEA) derived from L-lactic acid and α-alanine have been synthesized by melting copolymerization with p-toluenesulfonic acid (TSA) with stannous chloride (SnCl2) as catalyst. The products were analyzed by NMR, FT IR techniques. The effects of the content of α-alanine (L-Ala) on the copolymers structure were studied. Being the phosphate buffered saline (pH=7.2) as the degradation solution, the degradation rate speed up with the increasing the content of the α-alanine.
Kunyuan Gao, Shaoxiong Zhou, Xinqing Zhao
L. Liu et al., "Synthesis, Microstructure and Properties of Poly(L-Lactic Acid-Co-α-Alanine) Obtained by Direct Melting Copolymerization", Materials Science Forum, Vol. 685, pp. 390-393, 2011