Chemical-Hydrothermal Synthesis of Zr-Containing Titanium Oxide Film on CP-Ti

Abstract:

Titanium and its alloys have been employed in bone plates/screws, which must be removed after recovery. Conduction of bone occurs on the surface of Ti alloys that reside in the body for a long period. This can lead to re-fracture of cured bone in removal operations. On the other hand, bone has been reported not to be formed on the surface of Zr alloys. The purpose of this study was to synthesize Zr-containing TiO₂ film on commercial purity titanium (CP-Ti) by chemical-hydrothermal treatment. In addition, apatite formation on the films in Hanks’ solution and bone conduction in the tibiae of rats were also investigated. CP-Ti substrates were chemically treated with H₂O₂/HNO₃ aqueous solutions at 353 K for 20 min. The substrates were hydrothermally treated with ZrOCl₂/NH₃/hydroxy acid aqueous solutions in a Teflon-lined autoclave at 453 K for 12 h. The hydroxy acid was selected to be C₃H₆O₃ (lactic acid), C₄H₆O₆ (tartaric acid) or C₆H₈O₇ (citric acid). In the hydrothermal treatment without hydroxy acid, the surface product was anatase-type TiO₂. In contrast, when hydroxy acid was added the surface of Ti was covered homogeneously with a Zr-containing TiO₂ film. Some of the Zr (OH)₄ sol in the solution is thought to have dissolved into the solution by coordinate bonding with hydroxy acid carboxyl groups, leading to incorporation of Zr as ZrO₂ into the TiO₂. The product films suppressed the apatite precipitation in the Hanks’ solution soaking. In animal test, the small amount of ZrO₂ effectively suppressed the bone conduction.

• Periodical: Materials Science Forum (Volumes 783-786)
• Pages: 1383-1388
• DOI: https://doi.org/10.4028/www.scientific.net/MSF.783-786.1383
• Online since: May 2014
• Authors: Masato Ueda*, Masahiko Ikeda
• Keywords: Bioinert, Biomaterial, Hydrothermal Treatment, Surface Modification, Zirconia (ZrO₂)

References

[1] T. Hanawa, S. Hiromoto, K. Asami, O. Okuno and K. Asaoka, Surface Oxide Films on Titanium Alloys Regenerated in Hanks' Solution, Mater. Trans. 43 (2002) 3000-3004.

DOI: 10.2320/matertrans.43.3000

[2] L. Saldaña, A. Méndez-Vilas, L. Jiang, M. Multigner, J.L. González-Carrasco, M.T. Pérez-Prado, M.L. González-Martín, L. Munuera and N. Vi laboa, In vitro biocompatibility of an ultrafine grained zirconium, Biomaterials 28 (2007) 4343-4354.

DOI: 10.1016/j.biomaterials.2007.06.015

[3] P. Thomsen, C. Larsson and L.E. Ericson, L. Sennerby, J. Lausmaa and B. Kasemo, Structure of the interface between rabbit cortical bone and implants of gold, zirconium and titanium, J. Mater. Sci: Mater. In Medicine 8 (1997) 653-665.

DOI: 10.1023/a:1018579605426

[4] M. Uchida, H.M. Kim, F. Miyaji, T. Kokubo and T. Nakamura, Apatite formation on zirconium metal treated with aqueous NaOH, Biomaterials 23 (2002) 313-317.

DOI: 10.1016/s0142-9612(01)00110-7

[5] M. Ueda, R. Matsunaga, M. Ikeda and M. Ogawa, Hydrothermal crystallization of TiO2 gel films on Ti substrates and Formability of hydroxyapatite, Mater. Trans. 49 (2008) 1706-1709.

DOI: 10.2320/matertrans.mrp2008132

[6] M. Ueda, M. Ikeda and M. Ogawa, Chemical-hydrothermal combined surface modification of titanium for improvement of osteointegration, Mater. Sci. Eng. C 29 (2009) 994-1000.

DOI: 10.1016/j.msec.2008.09.002

[7] M. Ueda, Y. Sasaki, M. Ikeda and M. Ogawa, Hydrothermal synthesis of bioinert oxide film on Ti substrates, Mater. Trans. 50 (2009) 2104-2107.

DOI: 10.2320/matertrans.m2009112

[8] M. Ueda, Y. Sasaki, M. Ikeda, M. Ogawa, W. Fujitani and T. Nakano, Hydrothermal synthesis of bioinert ZrO2-TiO2 film on Ti substrates and proliferation of osteoblast-like cells, Mater. Trans. 50 (2009) 2147-2153.

DOI: 10.2320/matertrans.maw200910