Heparin Modified Temperature-Sensitive Hydrogels and Biocompatibility Research

Ning Yang; Lu Shi; Yi Bin Guo; Hao Zhang; Li Chen

doi:10.4028/www.scientific.net/MSF.809-810.527

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HomeMaterials Science ForumMaterials Science Forum Vols. 809-810Heparin Modified Temperature-Sensitive Hydrogels...

Heparin Modified Temperature-Sensitive Hydrogels and Biocompatibility Research

Abstract:

Chitosan/Heparin (CS/Hep) modified temperature sensitive hydrogels of γ-PGA were prepared by layer-by-layer self-assembly process. The chemical structure of the hydrogels and the surface elements were characterized by FT-IR spectrograph, XPS and TBO staining. The biocompatibility of the CS/Hep modified ploy (γ-PGA-co-NIPAAm) hydrogels were analyzed by the experiments of cell adhesion, cell proliferation and low-temperature induced cell detachment. A temperature-sensitive hydrogels carrier that could specific binding to growth factor was prepared in this research.

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2014 China Functional Materials Technology and Industry Forum

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Periodical:

Materials Science Forum (Volumes 809-810)

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527-532

DOI:

https://doi.org/10.4028/www.scientific.net/MSF.809-810.527

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Online since:

December 2014

Authors:

Ning Yang*, Lu Shi, Yi Bin Guo, Hao Zhang, Li Chen

Keywords:

Chitosan, Growth Factor , Heparin, N-NIPAAm, γ-PGA

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