A Critical Review on Zinc Oxide Nanoparticles (ZnO NPs) Bio Applications and Toxicities Mechanisms

Abstract:

In contrast to bulk materials, nanoparticles, which are distinguished by their extremely small size and remarkable surface area-to-volume ratio, have unique physical and chemical properties. Among the several metal-oxide nanoparticles, green zinc oxide nanoparticles have drawn a lot of interest because of their wide range of uses, including antibacterial, antifungal, antimicrobial, and anticancer activities. To assess the potential of zinc oxide nanoparticles in developing domains like bioapplications, this thorough investigation offers insights into the shape and structure of ZnO NPs as well as their characteristics and attributes using characterisation procedures. This work is novel because it carefully examines various synthesis techniques for zinc oxide nanoparticles, provides a thorough understanding of their chemical and biological complexities, and investigates how these nanoparticles' special properties can revolutionise this field. Through this investigation, we want to clarify the complexities of synthesis while also illuminating the wide range of uses and constraints of zinc oxide nanoparticles, offering a path forward for further nanotechnology research and development.

• Periodical: Nano Hybrids and Composites (Volume 48)
• Pages: 11-27
• DOI: https://doi.org/10.4028/p-H2r03N
• Online since: November 2025
• Authors: Haia H. Aldosari*
• Keywords: Antibacterial Activity, Anticancer Activity, Antimicrobial, Hazard, Toxicity Mechanism, ZnONPs

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