Synthesis of Phosphate Phases on Polysaccharide Template

Abstract:

New method of synthesis of biocompatible, biodegradable and nontoxic composite materials based on polysaccharide chitosan and inorganic phosphate component will be presented in this work. Materials structure was changed by in situ transformation of phosphate phases. Transformation of initial precursors to hydroxyapatite as one of the most stable phosphate phase occurred as a result of thermal and alkaline treatment. XRD and SEM methods were applied to investigate structure and morphology of obtained samples.

• Periodical: Solid State Phenomena (Volume 312)
• Pages: 314-318
• DOI: https://doi.org/10.4028/www.scientific.net/SSP.312.314
• Online since: November 2020
• Authors: Vladimir E. Silant'ev*, Vladimir S. Egorkin, Larisa A. Zemskova, Sergey L. Sinebryukhov, Sergey V. Gnedenkov
• Keywords: Chitosan, Composite, Controlled Synthesis, Hydroxyapatite, Phosphate Phases, Polysaccharide, Transformation

References

[1] D.W. Lee, H. Lim, H.N. Chong, W.S. Shim, Advances in chitosan material and its hybrid derivatives: a review, The open biomaterials journal. 1 (2009) 10-20.

DOI: 10.2174/1876502500901010010

[2] K.Z. Elwakeel, Environmental application of chitosan resins for the treatment of water and wastewater: a review, J. Disper. Sci. Technol. 31 (2010) 273-288.

[3] M.M. Reddy, S. Vivekanandhan, M. Misra, S.K. Bhatia, A.K. Mohanty, Biobased plastics and bionanocomposites: current status and future opportunities, Prog. Polym. Sci. 38 (2013) 1653-1689.

DOI: 10.1016/j.progpolymsci.2013.05.006

[4] S.M. Barinov, Calcium phosphate-based ceramic and composite materials for medicine, Russ. Chem. Rev. 79 (2010) 13-29.

DOI: 10.1070/rc2010v079n01abeh004098

[5] D. Boudemagh, P. Venturini, S. Fleutot, F. Cleymand, Elaboration of hydroxyapatite nanoparticles and chitosan/hydroxyapatite composites: a present status, Polym. Bull. (2018) https://doi.org/10.1007/s00289-018-2483-y.

DOI: 10.1007/s00289-018-2483-y

[6] A. Rogina, M. Ivanković, H. Ivanković, Preparation and characterization of nano-hydroxyapatite within chitosan matrix, Mat. Sci. Eng. C. 33 (2013) 4539-4544.

DOI: 10.1016/j.msec.2013.07.008

[7] J. Chen, K. Nan, S. Yin, Y. Wan, T. Wu, Q. Zhang, Characterization and biocompatibility of nanohybrid scaffold prepared via in situ crystallization of hydroxyapatite in chitosan matrix, Colloid. Surface. B. 81 (2010) 640-647.

DOI: 10.1016/j.colsurfb.2010.08.017

[8] R. Kumar, K.H. Prakash, P. Cheang, L. Gower, K.A. Khor, Chitosan-mediated crystallization and assembly of hydroxyapatite nanoparticles into hybrid nanostructured films, J. R. Soc. Interface. 5 (2008) 427-439.

DOI: 10.1098/rsif.2007.1141

[9] D. Gopi, S. Nithiya, E. Shinyjoy, L. Kavitha, Spectroscopic investigation on formation and growth of mineralized nanohydroxyapatite for bone tissue engineering applications, Specterochim. Acta A. 92 (2012) 194-200.

DOI: 10.1016/j.saa.2012.02.069

[10] A. Zima, Hydroxyapatite-chitosan based bioactive hybrid biomaterials with improved mechanical strength, Spectrochim. Acta A. 193 (2018) 175-184.

DOI: 10.1016/j.saa.2017.12.008

[11] J. Redepenning, G. Venkataraman, J. Chen, N. Stafford, Electrochemical preparation of chitosan/hydroxyapatite composite coatings on titanium substrates, J. Biomed. Mater. Res. A. 66A (2003) 411-416.

DOI: 10.1002/jbm.a.10571

[12] J. Kumirska, M. Czerwicka, Z. Kaczynski, A. Bychowska, K. Brzozowski and others, Application of spectroscopic methods for structural analysis of chitin and chitosan, Mar. Drugs. 8 (2010) 1567-1636.

DOI: 10.3390/md8051567

[13] S. Sathiyavimal, S. Vasantharaj, F. LewisOscar, A. Pugazhendhi, R. Subashkumar, Biosynthesis and characterization of hydroxyapatite and its composite (hydroxyapatite-gelatin-chitosan-fibrin-bone ash) for bone tissue engineering applications, Int. J. Biol. Macromol. 129 (2019) 844-852.

DOI: 10.1016/j.ijbiomac.2019.02.058