Using the multi-body simulation software SIMPACK as platform, a whole CHANGHE mini-car model was built. A fuzzy controller was adopted based on MATLAB/SIMULINK software to control the full car model. Pulse input running test simulation was carried out under co-simulation of SIMAT. The results showed that compared to passive suspension, with the speed 40km/h, the body vertical acceleration, body pitch angular velocity, standard deviation and peak were respectively decreased by 10.76%, 18.03% and 20.48%, 12.13%. The semi-active suspension system with fuzzy controller had better performance than passive suspension, reduced vibration effectively and improved automotive ride comfort.