In this study, Camphor leaves for the experimental materials, the activated composition was extracted by water, its consistency was 10%, and so the water extract was namely reagent A. The reagent B was obtained from added 5% MUF resins in reagent A, and the reagent C was obtained from added 10% MUF resins in reagent A. The Moso bamboo was treated respective by reagent A, reagent B, reagent C through vacuum/pressure process and the ability of resisted mould and mildew was tested. The results showed: The decay resistance of treated was stronger clearly than control, the weight lost rate was between 4% and 7%, it was up to the high anti-decay level. The decay resistance of treated by reagent B was strongest, so the appropriate MUF resins had function of fixation agent. The MOE and MOR of treated bamboo was almost equation to control. And the MOE and MOR of B and C was higher than control and A. It was feasible methods that the water extract of Camphor leaves was used to be a natural preservative. It was safe to human, animal, environment and the treated bamboo was an environmental friendly material.