Synthesis and Potent Biological Activity of 1-Sulfonyl Substituted Imidazole and Benzo[d]imidazole Compounds

Abstract:

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A new series of 1-sulfonly substituted imidazole compounds (containing 19 compounds) were synthesized and characterized by 1HNMR, 13CNMR and HRMS. 2d, 2e, 2h, 2i showed promising activities in animal test (in rats) for anti-inflammation. 2k - 2t were used in Chemokine Receptors CXCR4 receptor agonist Calcium assay showed no activities.

Info:

Periodical:

Advanced Materials Research (Volumes 236-238)

Edited by:

Zhong Cao, Yinghe He, Lixian Sun and Xueqiang Cao

Pages:

2570-2573

DOI:

10.4028/www.scientific.net/AMR.236-238.2570

Citation:

Y. J. Ren et al., "Synthesis and Potent Biological Activity of 1-Sulfonyl Substituted Imidazole and Benzo[d]imidazole Compounds", Advanced Materials Research, Vols. 236-238, pp. 2570-2573, 2011

Online since:

May 2011

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Price:

$35.00

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