Synthesis and Potent Biological Activity of 1-Sulfonyl Substituted Imidazole and Benzo[d]imidazole Compounds

Yu Jie Ren; Fan Hong Wu; Chun Feng Shu; Ma Liu

doi:10.4028/www.scientific.net/AMR.236-238.2570

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 236-238Synthesis and Potent Biological Activity of...

Synthesis and Potent Biological Activity of 1-Sulfonyl Substituted Imidazole and Benzo[d]imidazole Compounds

Abstract:

A new series of 1-sulfonly substituted imidazole compounds (containing 19 compounds) were synthesized and characterized by ¹HNMR, ¹³CNMR and HRMS. 2d, 2e, 2h, 2i showed promising activities in animal test (in rats) for anti-inflammation. 2k - 2t were used in Chemokine Receptors CXCR4 receptor agonist Calcium assay showed no activities.

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Periodical:

Advanced Materials Research (Volumes 236-238)

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2570-2573

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.236-238.2570

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Online since:

May 2011

Authors:

Yu Jie Ren, Fan Hong Wu, Chun Feng Shu, Ma Liu

Keywords:

Rat Anti-Inflammation, Sulfonyl Imidazole, Synthesis

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DOI: 10.1023/a:1015133508283

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