Improved Endothelialisation on Nanostructured Surfaces

Cenk Aktas; Ayman Haidar; Marina Martinez Miró; Eva Dörrschuck; Juseok Lee; Michael Veith; Hashim Abdul Khaliq

doi:10.4028/www.scientific.net/AMR.324.105

Paper Titles

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Influence of Magnetron Effect on Barium Hexaferrite Thin Layers
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Effect of Deposition Time on Physical Properties of Nanocrystallized SnS Zinc Blend Thin Films Grown by Chemical Bath Deposition
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Improved Endothelialisation on Nanostructured Surfaces
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Oxygen-Induced Formation of Nanopyramids on W(111)
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A Nano-Particle Synthesis Technology Dedicated to Solar Cells Applications
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Effect of the Ball Milling Conditions, under Air, on the Preliminary Hydriding Properties of the Mixtures Mg-x Wt% Graphite. Role of Solvent
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Influence of Experimental Parameters on the Synthesis of Gold Nanoparticles by Electroless Deposition
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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 324Improved Endothelialisation on Nanostructured...

Improved Endothelialisation on Nanostructured Surfaces

Abstract:

Abstract . Topography plays a major role on surface-cell interaction beside the surface chemistry. We investigated the effect of the nanotopography on vascular cell adhesion and proliferation in order to improve endothelialisation for restenosis treatment. In this context, Al2O3 nanowires (NWs) composed of a stable Al2O3 shell and an Al core were synthesized by chemical vapour deposition (CVD) of the molecular precursor (tBuOAlH2)2. After the detailed material characterization, human umbilical vein endothelial cells (HUVEC) and human umbilical vein smooth muscle cells (HUVSMC) were seeded and cultivated on these surfaces. Our preliminary results showed that there is a preference of HUVEC adhesion on NWs in comparison to that of HUVSMC. The control of the cell–surface interaction by the topography may represent a key issue for the future stent material design.

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Periodical:

Advanced Materials Research (Volume 324)

Pages:

105-108

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.324.105

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Online since:

August 2011

Authors:

Cenk Aktas, Ayman Haidar, Marina Martinez Miró, Eva Dörrschuck, Juseok Lee, Michael Veith, Hashim Abdul Khaliq

Keywords:

Cell-Surface Interactions, CVD, Nanowire, Restenosis

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