Preparation and Characterization of Novel Methyl Acrylate
Salvianolic acid B has many important pharmacological activities. A novel synthetic route of methyl acrylate derivative—an important intermediate to synthesize salvianolic acid B, was designed, and the target compound was prepared in seven steps of reactions with 2-bromo-3-hydroxy-4-methoxybenzaldehyde as major starting material. Its and other four important unreported intermediates’ structures were characterized by IR, 1H NMR, MS, etc.
Y. E. Guo et al., "Preparation and Characterization of Novel Methyl Acrylate", Advanced Materials Research, Vols. 343-344, pp. 1236-1241, 2012