Totally Biodegradable and Osteoconductive Composite Material Consisting of Polyhydroxybutyrate and Tricalcium Phosphate for Bone Tissue Repair

Abstract:

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Totally biodegradable and osteoconductive composite material consisting of polyhydroxybutyrate (PHB) and β-tricalcium phosphate (β-TCP) was manufactured for bone tissue repair. The composite production process was optimized with the help of differential scanning calorimetry (DSC) analyses. Thermogravimetric analyses (TGA) indicated that intended compositions for TCP/PHB composite could be achieved through this manufacturing route. Scanning electron microscopic (SEM) examinations revealed that TCP/PHB composite containing up to 40 vol.% of β-TCP had satisfactory distribution of micron-sized TCP particles in the composite. The good-quality composite will be further investigated in in vitro and in vivo experiments.

Info:

Periodical:

Advanced Materials Research (Volumes 47-50)

Edited by:

Alan K.T. Lau, J. Lu, Vijay K. Varadan, F.K. Chang, J.P. Tu and P.M. Lam

Pages:

1395-1398

DOI:

10.4028/www.scientific.net/AMR.47-50.1395

Citation:

Y. Liu and M. Wang, "Totally Biodegradable and Osteoconductive Composite Material Consisting of Polyhydroxybutyrate and Tricalcium Phosphate for Bone Tissue Repair", Advanced Materials Research, Vols. 47-50, pp. 1395-1398, 2008

Online since:

June 2008

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$35.00

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