Totally Biodegradable and Osteoconductive Composite Material Consisting of Polyhydroxybutyrate and Tricalcium Phosphate for Bone Tissue Repair
Totally biodegradable and osteoconductive composite material consisting of polyhydroxybutyrate (PHB) and β-tricalcium phosphate (β-TCP) was manufactured for bone tissue repair. The composite production process was optimized with the help of differential scanning calorimetry (DSC) analyses. Thermogravimetric analyses (TGA) indicated that intended compositions for TCP/PHB composite could be achieved through this manufacturing route. Scanning electron microscopic (SEM) examinations revealed that TCP/PHB composite containing up to 40 vol.% of β-TCP had satisfactory distribution of micron-sized TCP particles in the composite. The good-quality composite will be further investigated in in vitro and in vivo experiments.
Alan K.T. Lau, J. Lu, Vijay K. Varadan, F.K. Chang, J.P. Tu and P.M. Lam
Y. Liu and M. Wang, "Totally Biodegradable and Osteoconductive Composite Material Consisting of Polyhydroxybutyrate and Tricalcium Phosphate for Bone Tissue Repair", Advanced Materials Research, Vols. 47-50, pp. 1395-1398, 2008