Totally Biodegradable and Osteoconductive Composite Material Consisting of Polyhydroxybutyrate and Tricalcium Phosphate for Bone Tissue Repair

Ya Liu; Min Wang

doi:10.4028/www.scientific.net/AMR.47-50.1395

Paper Titles

An Experimental and Computational Study on Zn-Substituted Hydroxyapatite
p.1379

Biocompatibility and Osteogenesis of Calcium Phosphate Cement Scaffolds for Bone Tissue Engineering
p.1383

Electrochemical Deposition of Fluoridated Calcium Phosphate Thin Film on Titanium Substrates
p.1387

Deformation and Fracture of Bone Analogue Biomaterials Having Different Polymer Matrices
p.1391

Totally Biodegradable and Osteoconductive Composite Material Consisting of Polyhydroxybutyrate and Tricalcium Phosphate for Bone Tissue Repair
p.1395

In Vitro Degradation and Protein Adsorption Characteristics of PHBV/PLLA Blends and PHBV/PLLA-Based Tissue Engineering Scaffolds
p.1399

Characteristics and Chemical Stability of the Bioactive Titania Layer Formed on Ti, Ti-6Al-4V and NiTi SMA through a Low Temperature Oxidation Process
p.1403

Investigation of Platelet Adhesion Behavior on Si-N-O Films Synthesized by Unbalanced Magnetron Sputtering
p.1407

Adsoption CD34 Antibody onto the Col/Hep Coating Film on Titanium to Improve Cytocompatibility of Titanium
p.1411

HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 47-50Totally Biodegradable and Osteoconductive...

Totally Biodegradable and Osteoconductive Composite Material Consisting of Polyhydroxybutyrate and Tricalcium Phosphate for Bone Tissue Repair

Abstract:

Totally biodegradable and osteoconductive composite material consisting of polyhydroxybutyrate (PHB) and β-tricalcium phosphate (β-TCP) was manufactured for bone tissue repair. The composite production process was optimized with the help of differential scanning calorimetry (DSC) analyses. Thermogravimetric analyses (TGA) indicated that intended compositions for TCP/PHB composite could be achieved through this manufacturing route. Scanning electron microscopic (SEM) examinations revealed that TCP/PHB composite containing up to 40 vol.% of β-TCP had satisfactory distribution of micron-sized TCP particles in the composite. The good-quality composite will be further investigated in in vitro and in vivo experiments.