A DC Voltage Driven Flow-Through Electroporation Microchip

Qiao Le Zhao; Yu Cheng Lin; Qin Gan Huang

doi:10.4028/www.scientific.net/AMR.60-61.44

Paper Titles

Scanning Ion Conductance Microscopy and its Applications in Nanobiology and Nanomedicine
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Analysis of Temperature Effects on a Fully-Symmetrical Micromachined Gyroscope
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The I-V Characteristics and Percolation Threshold of the Cement-Based Materials Filled with Multi-Walled Carbon Nanotubes
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Design of a Hybrid-Type Electrostatically Driven Microgripper Integrated Vacuum Tool
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A DC Voltage Driven Flow-Through Electroporation Microchip
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Detection for Spring Constant of Microcantilevers in Atomic Force Microscopy Based on Frequency Measurements
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Photochemical Synthesis of Gold Nanostructures in Different Solvents
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MEMS Dielectrophoresis Device for Osteoblast Cell Stimulation
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An Excellent Platinum Piezoresistive Pressure Sensor Using Adhesive Bonding with SU-8
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A DC Voltage Driven Flow-Through Electroporation Microchip

Abstract:

Differing with the traditional way to perform electroporation (EP) by using the DC electrical pulse, this paper proposes a new EP system by applying continuous DC voltages to generate proper EP electric field strengths utilizing the shape change of the channel. The fabrication of chip and set-up of system are clearly described and simulations also carried out utilizing CFD-ACE to study the electric field strength distribution and the time span when fluid passes through different electric field strengths. The fabrication of the proposed EP system is quite simple and low-cost.