Scanning Ion Conductance Microscopy and its Applications in Nanobiology and Nanomedicine

Li Ping Liu; Yun Dou Wang; Yan Jun Zhang

doi:10.4028/www.scientific.net/AMR.60-61.27

Paper Titles

Uniaxial Stress Dependence of Electrical Properties of Ulrathin Ballistic P-Type Silicon Nanotransistor
p.6

Optical and Electrical Properties of SnS: Ag Films as Solar Cell Absorbers
p.11

WO₃ Nanostructures Synthesized by a Sonochemical Strategy
p.16

Metrology Method of Line Edge Roughness with Nanometer Scale Precision Using Atomic Force Microscopes
p.22

Scanning Ion Conductance Microscopy and its Applications in Nanobiology and Nanomedicine
p.27

Analysis of Temperature Effects on a Fully-Symmetrical Micromachined Gyroscope
p.31

The I-V Characteristics and Percolation Threshold of the Cement-Based Materials Filled with Multi-Walled Carbon Nanotubes
p.36

Design of a Hybrid-Type Electrostatically Driven Microgripper Integrated Vacuum Tool
p.40

A DC Voltage Driven Flow-Through Electroporation Microchip
p.44

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Scanning Ion Conductance Microscopy and its Applications in Nanobiology and Nanomedicine

Abstract:

In cell biology and medicine study, continuous high spatial resolution observations of living cells would greatly aid the elucidation of the relationship between structure and function of cells. The development of scanning probe microscopy (SPM) has opened up a new era of life science and has been used to develop a family of related methods that allow studying of cell structure and function on nanometer scale. Scanning ion conductance microscopy (SICM) is a new member of such SPM family and can be used to obtain high-resolution non-contact images of the surface of live cells under physiological conditions, and hence allows the relationship between cell microstructure and function to be probed. In this review, we concisely introduce the principles of SICM and its applications in nanobiology and nanomedicine.