Advanced Materials Research Vols. 634-638

Abstract: A small chemical library of quinolone acid derivatives were synthesized as potential HIV-1 integrase inhibitors and evaluated their inhibition to the strand transfer process of HIV-1 integrase. Their structures were characterized by NMR, MS and HRMS. The result indicates that quinolone acid derivatives having 3,4,5-trihydroxylated aromatic substituent on the N-1 position of quinolone ring exhibit good inhibition with IC50 of 2.6 μM.

Abstract: In a long period, silk fibroin is applied in the biomedical area. Following the development of biotechnical, its new functions are get found and developed. From the ordinary tissue engineering frame to high grade frame with drug buffer system, exploitations of silk fibroin are constantly introduced new. In our review, we summarized the applications of silk fibroin in tissue engineering and drug carrier area.

Abstract: The aerogel-type wood is prepared under crafts of dissolution of wood materials by 1 - propenyl -3- methylimidazolium ionic liquid and followed supercritical drying process. And then, cellulose fibers as supporting frame with incomplete three-dimensional cross-linked network are reformed after dissolution of aerogel-based timber. The reformed cellulose fibers possess microstructure that similar with light wood, stable chemical and physical properties, dry density of 0.221 g/cm3 and porosity over 87%. Additionally, the novel wood-based material achieved by green chemical treatment can continue to fix and store carbon absorbed during the growth stage of trees, and will also play a certain significance in areas of low-carbon and environmental protection.

Abstract: The low concentration of CO2 in the atmosphere is one of the main factors to restrict photosynthesis of C3 plants. The effect of KHCO3 on photosynthesis of eggplant seedlings was studied in order to improve photosynthesis of C3 plants. The results showed that KHCO3 could significantly enhance the photosynthetic rate of eggplant seedlings. 500mg/L KHCO3 was the most optimal concentration to improve photosynthetic rate of eggplant seedlings. KHCO3 could increase light saturation point, CO2 saturation point, carboxylase efficiency and lower CO2 compensate point of eggplant seedlings. KHCO3 could improve stomatal conductance and electron transport activity. There was phosphoenolpyruvate carboxylase (PEPC) in leaves of eggplant seedlings, but PEPC activity was low. KHCO3 could improve ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) activity and PEPC activity. From impact factors, HCO3- could enhance photosynthetic rate. K+ could raise stomatal conductance of eggplant seedlings. HCO3- could improve activity of PEPC . Both HCO3- and K+ could increase Rubisco activity.

Abstract: Six compounds were synthesized from the lanostane-type tetracyclic triterpenoid of trametenolic acid B with the aim of obtaining more active compounds, which were characterized by NMR, IR, ESI-MS and elemental analysis. Their cytotoxic activities were evaluated against the breast cancer cell line MD-AMB-231. The compound 3b exhibited the best anti-proliferative effect than trametenolic acid B and other derivatives with the IC50 of 17.78 µM.

Abstract: Utilization of locally abundant agro-waste Alpinia galanga (A. galanga) natural fibers in polyethylene (PE) was investigated. The results indicate that agro-waste fibers generally function as potential natural-organic fillers as well as show an attribute of reinforcement in PE-agro-waste composites at a certain fiber loading. Minimally reduced tensile strength from 28 MPa of unfilled PE, addition of agro-waste A. galanga natural fibers also resulted in reinforcement of up to 31 MPa at 6 wt% agro-waste fibers loading. Findings also reveal that alkali treatment was effective to impart surface modification of agro-waste A. galanga natural fibers and hence improved tensile strength, modulus of elasticity and thermal stability of PE-agro-waste composites.

Abstract: With tetrabutyl orthotitanate, hydrazine hydrate and aluminum chloride hexahydrate as original materials and pyridine as a template reagent, N/Al doped TiO2 (N-TiO2, Al-TiO2, Al-N-TiO2) mesoporous nanomaterials were successfully synthesized through a simple and environmentally friendly solid state reaction route. The textural properties of the samples were characterized by X-ray diffraction (XRD), high resolution transmission electron microscope (HRTEM), ultraviolet visible light spectroscopy (UV-Vis), X-ray photoelectron spectroscopy (XPS), Raman spectroscope and N2 adsorption-desorption at 77K. Moreover, the formation mechanism of the N/Al-doped TiO2 mesoporous material was proposed in presence of pyridine. It clearly shows that the microscopic structure of Al-N-TiO2 nanomaterial with crystal anatase phase is an irregular shape nanoparticle with size of 5~20 nm. N atoms as N3- states have been incorporated into the lattice of TiO2 or have been entered into the interstice of TiO2 lattice. Al ions occupy the sites of Ti in crystal lattices by isomorphous replacement. Either the doping of N or Al, or the co-doping of N and Al, it can effectively embarrass the crystal growth of TiO2. The specific surface area and the average pore diameter are the 138.4 m2/g and 1.9 nm, respectively. Interestingly, the UV-vis spectra display that the adsorption intensity of N-Al-TiO2 nanomaterial decreases in the order of N-Al-TiO2＞N-TiO2＞Al-TiO2.

Abstract: Ropivacaine hydrochloride was synthesized from 2-pipecolic acid by successive reaction with SOCl2 and 2,6-dimethylaniline at 40°C under ultrasonic irradiation to give (S)-N-(2,6-dimethylphenyl)-piperidin-2-carboxamide (4), and 4 was reacted with 1-bromopropane at 50°C for 1 h under ultrasonic irradiation. The effect of reaction solvent, temperature and time under ultrasonic irradiation were investigated. Compared with conventional methods, the main advantages of the present procedure are milder conditions, shorter reaction time and higher yields. The total yield was 63.1%, [α]25 D= – 6.7°(c = 2, H2O).

Abstract: Using fresh strawberry fruits as materials, the impact of using ultrasound to sterilize the process of strawberry wine was studied in this paper. In the experiment, the effects of different ultrasonic frequency, ultrasonic time and ultrasonic temperature in processing of strawberry wine were studied respectively. The results indicated that the treatment with supersonic procession of 40°C, 60min and 120W could get the best pH value of strawberry wine; the treatment with supersonic procession of 40°C, 45min, 80W could get the best total acidity value; the treatment with supersonic procession of 30°C, 45min, 120W could get the best Vc content value; the treatment with supersonic procession of 40°C, 45min, 100W could get the best sensory score of strawberry wine; treated with supersonic procession of 40°C, 30min, 100W, the microbic quantity of strawberry wine could be get the lowest value. Among them, ultrasonic power had a more significant effect on the pH and total acidity of strawberry wine, as well as ultrasonic temperature on the content of Vc and ultrasonic time on the sensory evaluation and microbial quantity.

Abstract: Silk fibroin （SF） hydrogels of the wild silkworm species Antheraea pernyi and Antheraea yamamai were obtained from aqueous SF solutions at room temperature. Both A. pernyi and A. yamamai solutions were slow to gelate. Hydrogels of the two species of wild silkworm were obtained rapidly following ultrasonicaton at 400–500 W. The secondary structure of the freeze-dried SF hydrogels was measured by X-ray diffraction and Fourier transform infrared spectroscopy. Ultrasonication did not change the main secondary structure of the hydrogels, but it accelerated the structural transformation of silk fibroin molecules from random coil or α helix to β sheet and reduced the gelation time.