Progesterone Side-Chain Cleavage by Aspergillus versicolor

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Abstract:

Side chain cleavage of progesterone occurred in the biotransformation by Aspergillus versicolor. The conversion products were purified by column chromatography with ether/EtOAc and characterized by spectroscopic methods including 1H NMR, 13C NMR, IR, UV, MS and physical constants such as melting point and optical rotation. Those conversion products were identified as testosterone, androstenedione and androstenediendione.

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Advanced Materials Research (Volumes 781-784)

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1164-1167

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September 2013

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© 2013 Trans Tech Publications Ltd. All Rights Reserved

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[1] T. Murohisa and M. Iida, Journal of Fermentation and Bioengineering Vol. 75 (1993), p.13.

Google Scholar

[2] S. Ahmad, S. K. Garg and B. N. Johri, Biotechnology Advances Vol. 10 (1992), p.1.

Google Scholar

[3] M. Vitas, D. Rozman, R. Komel and S. L. Kelly, Phytochemistry Vol. 40 (1995), p.73.

Google Scholar

[4] L. Cattel, O. Caputo, F. Viola and G. Balliano, Farmaco-Edizione Scientifica Vol. 10 (1980), p.843.

Google Scholar

[5] L. Wadhwa and K. E. Smith, Fems Microbiology Letters Vol. 192 (2000), p.179.

Google Scholar

[6] P. F. Hall, J Steroid Biochem Mol Biol Vol. 40(1991), p.527.

Google Scholar

[7] A.G. Kulkarni, S.S. Lele, P.R. Kulkarni. J Microbiol Biotechnol Vol. 86 (1998), p.510.

Google Scholar

[8] P. Fernandes, A. Cruz, B. Angelova, H. M. Pinheiro and J. M. S. Cabral, Enzyme and Microbial Technology Vol. 32(2003), p.688.

DOI: 10.1016/s0141-0229(03)00029-2

Google Scholar

[9] M. A. Faramarzi, M. T. Yazdi, M. Amini, F. A. Mohseni, G. Zarrini, A. Amani and A. Shafiee, World Journal of Microbiology & Biotechnology Vol. 20 (2004), p.657.

DOI: 10.1007/s11274-004-1003-4

Google Scholar

[10] M. E. Mostafa and A. A. Zohri, Folia Microbiol (Praha) Vol. 45 (2000), p.243.

Google Scholar

[11] A. C. Hunter, J. Elsorn, L. Ross and R. Barrett, Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids Vol. 1761 (2006), p.360.

Google Scholar

[12] A. C. Hunter and H. Bergin-Simpson, Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids Vol. 1771 (2007), p.1254.

DOI: 10.1016/j.bbalip.2007.07.001

Google Scholar

[13] A. C. Hunter, E. Coyle, F. Morse, C. Dedi, H. T. Dodd and S. -J. Koussoroplis, Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids Vol. 1791 (2009), p.110.

DOI: 10.1016/j.bbalip.2008.12.005

Google Scholar

[14] A. C. Hunter, H. Khuenl-Brady, P. Barrett, H. T. Dodd and C. Dedi, Journal of Steroid Biochemistry and Molecular Biology Vol. 118 (2010), p.171.

DOI: 10.1016/j.jsbmb.2009.12.003

Google Scholar

[15] D. N. Kirk, H. C. Toms, C. Douglas, K. A. White, K. E. Smith, S. Latif and R. W. P. Hubbard, Journal of the Chemical Society-Perkin Transactions 2 (1990), p.1567.

Google Scholar

[16] D. N. Kirk, B. W. Miller, S. A. Latif and D. J. Morris, Journal of Chemical Research-S (1989), p.164.

Google Scholar

[17] J. W. Blunt and J. B. Stothers, Organic Magnetic Resonance Vol. 9 (1977), p.439.

Google Scholar

[18] D. H. Peterson and H. C. Murray, Journal of the American Chemical Society Vol. 74 (1952), p.1871.

Google Scholar