Comparative Study about Cytotoxicity with CuO Engineered Nanoparticles, TiO2 Engineered Nanoparticles, CeO2 Engineered Nanoparticles, Single-Walled Carbon Nanotubes

Shao Kun Men; Xue Song Cao; Zhen Yu Wang

doi:10.4028/www.scientific.net/AMR.881-883.956

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Comparative Study about Cytotoxicity with CuO Engineered Nanoparticles, TiO₂ Engineered Nanoparticles, CeO₂ Engineered Nanoparticles, Single-Walled Carbon Nanotubes

Abstract:

Engineered nanoparticles have been extensively used in electronics, energy, materials and biomedical areas. Engineered nanoparticles with unique magnetic, luminescent, and catalytic properties can not only benefit human society, but also cause potentially harmful interactions with living systems. This study was aimed at assessing the cytotoxicity of CuO ENPs, TiO₂ ENPs, CeO₂ ENPs, SWCNTs in human lung epithelial cell line (A549). Herein, we performed a comprehensive study on the cytotoxicity of four different ENPs by examining the viability of A549 cells. The results showed that CuO ENPs could cause a highest dose-dependent cytotoxicity, SWCNTs were more toxic than TiO₂ ENPs and CeO₂ ENPs to A549 cells, TiO₂ ENPs induced a slight loss of cell viability at 100 mg/L and CeO₂ ENPs had no obvious cytotoxicity. These effects were dose related, and should be considered in the application of different areas of ENPs.

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Periodical:

Advanced Materials Research (Volumes 881-883)

Pages:

956-959

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.881-883.956

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Online since:

January 2014

Authors:

Shao Kun Men, Xue Song Cao, Zhen Yu Wang*

Keywords:

A549 Cell, CeO₂ ENPs, CuO ENPs, Cytotoxicity, SWCNTs, TiO₂ ENPs

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* - Corresponding Author

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