The Application of High Throughput Microarrays in the Screening Active Ingredients of Traditional Chinese Medicine

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Abstract:

The accurate detection of traditional Chinese medicine is significant for diagnosis, treatment and control for disease. There is an urgent need for the development of a rapid, simple, and accurate detection method. The high throughput microarray is recommended for use in all researches including those involving rare samples and expensive reagents. Due to the complexity of Chinese medicines interference and multi-target, multi-component, the advantages that sensitivity, reproducibility, and specificity of high-throughput microarrays make it become one of the effective research tools.

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Advanced Materials Research (Volumes 998-999)

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346-349

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July 2014

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© 2014 Trans Tech Publications Ltd. All Rights Reserved

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[1] Sze S C, Zhang K Y, Shaw P C, et al, A DNA microarray for differentiation of (Fengdou Shihu) by its 5S ribosomal DNA intergenic spacer region, Biotechnol Appl Biochem. 49 (2008) 149-154.

DOI: 10.1042/ba20070059

Google Scholar

[2] Xie Z Q, Liang G, Zhang L, et al, Molecular mechanisms underlying the cholesterol-lowering effect of Ginkgo biloba extract in hepatocytes: a comparative study with lovastatin, Acta Pharmacol Sin. 30 (2009) 1262-1275.

DOI: 10.1038/aps.2009.126

Google Scholar

[3] Woo JH, Li D, Wilsbach K, et al, Coix seed extract, a commonly used treatment for cancer in China, inhibits NFkappaB and protein kinase C signaling, Cancer Biol Ther. 6 (2007) 2005-(2011).

DOI: 10.4161/cbt.6.12.5168

Google Scholar

[4] Schreiber SL, Nicolaou KC, Davies K, Diversity-oriented organic synthesis and proteomics: new frontiers for chemistry & biology, Chem BioL. 9 (2002) 1-2.

Google Scholar

[5] Hara A, Lizuka N, Hamamoto Y, et al, lecular dissection of a medicinal herb with anti-tumor activity by oligonucleotide microarray, Life Sci. 9 (2005) 991-1002.

DOI: 10.1016/j.lfs.2005.01.018

Google Scholar

[6] Bian Q, Huang J H, Yang Zh, et al, ffects of active ingredients in three kidney-tonifying Chinese herbal drugs on gene expression profile of bone marrow stromal cells from a rat model of corticosterone-induced osteoporosis, Journal of Chinese Integrative Medicine. 9 (2011).

DOI: 10.3736/jcim20110211

Google Scholar