Preparation, Characterization and Optical Analysis of Chromium Doped 45S Bioactive Glass-Ceramic

Abstract:

The 45S Bioactive glass-ceramic (BG) and Chromium (Cr)-doped BG materials were successfully produced in this study. XRD, FTIR, and ICP-MS techniques were used to characterize the prepared materials. The XRD testing showed that all samples contained pure BG. Increased Cr ion inclusion shifted the BG diffraction peaks to a lower value of 2 Theta and increased crystallinity. FTIR was used to detect Si-O, P-O, and Ca-O functional groups. Cr ions steadily decreased the Ca-vibration mode area. The ultraviolet-visible spectrophotometry was used to measure the optical characteristics of pure and Cr BG-doped materials. The Cr-doped BG was green in colour, whereas the lab-synthesized BG was white. Two additional bands formed at 433 and 615 nm when Cr ions were doped into the BG structure. These bands may be caused by ⁴A₂ → ⁴T₁ and ⁴A₂ → ⁴T₂ electronic d-d transitions. The findings show that biomedical applications may exist for fluorescent probes manufactured from Cr-BG materials.

• Periodical: Journal of Biomimetics, Biomaterials and Biomedical Engineering (Volume 65)
• Pages: 59-66
• DOI: https://doi.org/10.4028/p-Pihx2j
• Online since: July 2024
• Authors: İsmail Seçkin Çardaklı*
• Keywords: Bioglass, Characterization, Chromium, Optical Properties

References

[1] E. Okay, A.C. Ozarslan, Ö. Başal, H. Cakıroglu, S. Yucel, K. Özkan, M.N. Doral, The Biocompatibility of a new type of 45S5 bioactive graft in a sheep model: a pilot study, Cureus, 15(7) (2023) e.41521.

DOI: 10.7759/cureus.41521

[2] N. Jafari, M. S. Habashi, A. Hashemi, R. Shirazi, N. Tanideh, A. Tamadon, Application of bioactive glasses in various dental fields, Biomaterials Research, 26 (2022) 31.

DOI: 10.1186/s40824-022-00274-6

[3] I. Ielo, G. Calabrese, G. de Luca, S. Conoci, Recent advances in hydroxyapatite-based biocomposites for bone tissue regeneration in orthopedics, International Journal of Molecular Sciences, 23(17) (2022) 9721.

DOI: 10.3390/ijms23179721

[4] R. M. Rad, A. Z. Alshemary, Z. Evis, D. Keskin, K. Altunbaş, A. Tezcaner, Structural and biological assessment of boron doped bioactive glass nanoparticles for dental tissue applications, Ceramics International, 44(8) (2018) 9854-9864.

DOI: 10.1016/j.ceramint.2018.02.230

[5] J. Bejarano, A.R. Boccaccini, C. Covarrubias, H. Palza, Effect of Cu-and Zn-doped bioactive glasses on the In vitro bioactivity, mechanical and degradation behavior of biodegradable PDLLA scaffolds, Materials, 13 (2020) 2908.

DOI: 10.3390/ma13132908

[6] A.B. Workie, E.M. Sefene, Ion-doped mesoporous bioactive glass: preparation, characterization, and applications using the spray pyrolysis method, RSC Advances, 12(3) (2022) 1592-1603.

DOI: 10.1039/d1ra06113e

[7] H. Manoochehri, M Ghorbani, M. M. Moghaddam, M. R. Nourani, P. Makvandi, E. Sharifi, Strontium doped bioglass incorporated hydrogel-based scaffold for amplified bone tissue regeneration, Scientific Reports, 12(1) (2022) 10160.

DOI: 10.1038/s41598-022-14329-0

[8] P. T. Bhattacharya, S.R. Misra, and M. Hussain, Nutritional aspects of essential trace elements in oral health and disease: an extensive review, Scientifica (Cairo), 2016 (2016) 5464373.

DOI: 10.1155/2016/5464373

[9] W. Roczniak, B. B. Dopierala, E. Cipora, A. J. Kolon, M. Konieczny, M. B. Roczniak, Analysis of the content of chromium in certain parts of the human knee joint, Int J Environ Res Public Health, 15(5) (2018) 1013.

DOI: 10.3390/ijerph15051013

[10] Y. Hua, S. Clark, J. Ren, N. Sreejayan, Molecular mechanisms of chromium in alleviating insulin resistance, The Journal of Nutritional Biochemistry, 23(4) (2012) 313-319.

DOI: 10.1016/j.jnutbio.2011.11.001

[11] R.A. Ngala, M.A. Awe, and P. Nsiah, The effects of plasma chromium on lipid profile, glucose metabolism and cardiovascular risk in type 2 diabetes mellitus. a case-control study, PloS one, 13(7) (2018) e0197977.

DOI: 10.1371/journal.pone.0197977

[12] E. Vafa, R. Bazargan-Lari and M.E. Bahrololoom, Synthesis of 45S5 bioactive glass-ceramic using the sol-gel method, catalyzed by low concentration acetic acid extracted from homemade vinegar, Journal of Materials Research and Technology, 10 (2021) 1427-1436.

DOI: 10.1016/j.jmrt.2020.12.093

[13] S. Tautkus, K. Ishikawa, R. Ramanauskas and A. Kareiva, Zinc and chromium co-doped calcium hydroxyapatite: sol-gel synthesis, characterization, behaviour in simulated body fluid and phase transformations, Journal of Solid State Chemistry, 284 (2020) 121202.

DOI: 10.1016/j.jssc.2020.121202

[14] A. Z. Alshemary, Y. F. Goh, I. Shakir, R. Hussain, Synthesis, characterization and optical properties of chromium doped β-Tricalcium phosphate, Ceramics International, 41(1, Part B) (2015) 1663-1669.

DOI: 10.1016/j.ceramint.2014.09.107

[15] H.O. Simila and A.R. Boccaccini, Sol-gel synthesis of lithium doped mesoporous bioactive glass nanoparticles and tricalcium silicate for restorative dentistry: comparative investigation of physico-chemical structure, antibacterial susceptibility and biocompatibility, Frontiers in Bioengineering and Biotechnology, 11 (2023) 1065597.

DOI: 10.3389/fbioe.2023.1065597

[16] M. Wakamura, H. Tanaka, Y. Naganuma, N. Yoshida, T. Watanabe, Surface structure and visible light photocatalytic activity of titanium–calcium hydroxyapatite modified with Cr (III), Advanced Powder Technology, 22(4) (2011) 498-503.

DOI: 10.1016/j.apt.2010.10.012

[17] T.S. de Araujo, Z. S. Macedo, P. A. S. C. de Oliveira, M. E. G. Valerio Production and characterization of pure and Cr 3+-doped hydroxyapatite for biomedical applications as fluorescent probes, Journal of Materials Science, 42 (2007) 2236-2243.

DOI: 10.1007/s10853-006-0536-3