Assessment on the Release of Magnetite Nanoparticles Embedded with PVA Nanofiber in Hydrodynamics

Abstract:

Magnetite nanoparticle with average size 7-10 nm was embedded with biocompatible polyvinyl alcohol nanofiber and the average diameter of nanofiber is 115 nm. The nanofiber was further assembled over polymeric mesh to analyse the release mechanism of nanoparticles from polymer nanofiber. A hydrodynamics setup was constructed to study this system. Prior to hydrodynamics the nanofiber was allowed to react with water in static mode and observed that the magnetite nanoparticles were released from the nanofiber with increase in time. UV-Visible Spectrophotometer is used for analysis of absorbance and transmittance of polyvinyl alcohol-magnetite nanoparticles solution, nanofiber and films. High-resolution scanning electron microscopy is used to analyze the dimension of nanofiber; High-resolution transmission electron microscopy is used to find the size of magnetite nanoparticles. Here, an online spectroscopic technique was used to study the release mechanism of nanoparticles from nanofibers samples of different layers during hydrodynamics. The results reveal that the quantity of magnetite nanoparticles can be controlled by embedding into nanofibers during hydrodynamics. Also, the spectroscopic results indicate the quantity of nanoparticles released from nanofiber. This mechanism can be utilized to control the required quantity of nanoparticles to release at particular location through a polymer mesh assembly.

• Periodical: Journal of Nano Research (Volume 41)
• Pages: 31-41
• DOI: https://doi.org/10.4028/www.scientific.net/JNanoR.41.31
• Online since: May 2016
• Authors: Vikram Srinivas*, Vasanthakumari Raju
• Keywords: Controlled Release, Magnetic Nanoparticles, Nanofiber, PVA, Spectroscopy

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