Synthesis CaTiO₃: Er³⁺ Films on Titanium by Anodization and Hydrothermal Method for Drug Delivery Applications

Abstract:

To address the limitations of traditional drug delivery, CaTiO₃:Er³⁺ film (CTO:Er) is studied as a promising material for drug delivery systems. With regard to the excellent biocompatibility and physicochemical properties, CTO:Er prepared by a facile electrochemical anodizing process combined with a hydrothermal method has been used to fabricate new drug-releasing implants for localized drug delivery. This review discusses the development of CTO:Er applied in localized drug delivery systems, which uses nano drug curcumin for testing. Furthermore, with the special structure of the material, it meets the needs of drug absorption and delivery. Finally, the review concludes with the advances of CTO:Er for controlled drug delivery and corresponding prospects in the future.

• Periodical: Key Engineering Materials (Volume 1002)
• Pages: 63-69
• DOI: https://doi.org/10.4028/p-RfK2xM
• Online since: December 2024
• Authors: Nguyen Thi Thanh Tuyen, Le Thi Thu Lan, Vuong Hung Pham*
• Keywords: CaTiO₃: Er³⁺ Film, Drug Delivery, Electrochemical Anodizing, Hydrothermal Method

References

[1] M. N. Rahaman et al., "Bioactive glass in tissue engineering," Acta Biomater., 7 (2011) 2355–2373.

[2] Z. Gou, J. Chang, and W. Zhai, "Preparation and characterization of novel bioactive dicalcium silicate ceramics," J. Eur. Ceram. Soc., 25 (2005) 1507–1514.

DOI: 10.1016/j.jeurceramsoc.2004.05.029

[3] M. N. Salimi and A. Anuar, "Characterizations of biocompatible and bioactive hydroxyapatite particles," Procedia Eng., 53 (2013) 192–196.

DOI: 10.1016/j.proeng.2013.02.025

[4] J. Jeong, J. H. Kim, J. H. Shim, N. S. Hwang, and C. Y. Heo, "Bioactive calcium phosphate materials and applications in bone regeneration," Biomater. Res., 23 (2019) 1–11.

DOI: 10.1186/s40824-018-0149-3

[5] H. Mohammadi et al., "Bioinorganics in bioactive calcium silicate ceramics for bone tissue repair: Bioactivity and biological properties," J. Ceram. Sci. Technol., 5 (2014) 1–12.

[6] E. Cerrato, C. Gionco, I. Berruti, F. Sordello, P. Calza, and M. C. Paganini, "Rare earth ions doped ZnO: Synthesis, characterization and preliminary photoactivity assessment," J. Solid State Chem., 264 (2018) 42–47.

DOI: 10.1016/j.jssc.2018.05.001

[7] M. Prathap Kumar, G. A. Suganya Josephine, G. Tamilarasan, A. Sivasamy, and J. Sridevi, "Rare earth doped semiconductor nanomaterials and its photocatalytic and antimicrobial activities," J. Environ. Chem. Eng., 6 (2018) 3907–3917.

[8] X. L. Pang, C. H. Jia, G. Q. Li, and W. F. Zhang, "Bright white upconversion luminescence from Er3+-Tm 3+-Yb3+ doped CaSnO3 powders," Opt. Mater. (Amst)., 34 (2011) 234–238.

DOI: 10.1016/j.optmat.2011.08.019

[9] S. Heer, K. Kömpe, H. U. Güdel, and M. Haase, "Highly efficient multicolour upconversion emission in transparent colloids of lanthanide-doped NaYF4 nanocrystals," Adv. Mater., 16, (2004) 2102–2105.

DOI: 10.1002/adma.200400772

[10] R. Yun et al., "Upconversion luminescence and temperature sensing properties in LiGd(WO4)2: Er3+, Yb3+, Nd3+ microparticles under 785 nm excitation," Ceram. Int., 47 (2021) 16062–16069.

DOI: 10.1016/j.ceramint.2021.02.180

[11] N. T.T. Tuyen, T.Q. Tuan, L. V. Toan, L.T. Tam and V.H. Pham., "Synthesis of Up-Conversion CaTiO3: Er3+ Films on Titanium by Anodization and Hydrothermal Method for Biomedical Applications," Materials, 17 (2024) 3376.

DOI: 10.3390/ma17133376

[12] H. Liu et al., "A Fibrous Localized Drug Delivery Platform with NIR-Triggered and Optically Monitored Drug Release," Langmuir, 32 (2016) 9083–9090.

DOI: 10.1021/acs.langmuir.6b02227

[13] D. H. Quan et al., "Synthesis of TiO2 Nanotubes for Improving the Corrosion Resistance Performance of the Titanium Implants," VNU J. Sci. Math. - Phys., 38 (2022) 61–68.