Drug Loaded Porous Hydroxyapatite and Its In Vitro Release
Porous hydroxyapatite coated with mesoporous silica has been utilized as the matrix for controlled drug delivery. TEM observation confirms the pore size of mesoporous silica scatters about 50 Å. Porous hydroxyapatite was coated with mesoporous silica via sol-gel process. Ibuprofen and was loaded into the pores of mesoporous silica, and controlled release profiles were studied by soaking the samples in a simulated body fluid using a UV-VIS spectrophotometer.
Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.
Y. Kim et al., "Drug Loaded Porous Hydroxyapatite and Its In Vitro Release ", Key Engineering Materials, Vols. 284-286, pp. 423-426, 2005