Drug Loaded Porous Hydroxyapatite and Its In Vitro Release

Y. Kim; B.G. Song; Soo Ryong Kim; Kwang Jin Kim

doi:10.4028/www.scientific.net/KEM.284-286.423

Paper Titles

Porous HA Scaffolds for Drug Releasing
p.407

In Vitro Behavior of Yttrium Silica Sol-Gel Microspheres
p.411

Antibiotic Loaded Sol-Gel Derived Calcium Phosphate/Silica Composite for Bone Regeneration
p.415

Fabricating Hydroxyapatite Spherulites with Characteristic Microporous Structure by Chitin Sol Emulsified in Oil and Gelatinized In Situ
p.419

Drug Loaded Porous Hydroxyapatite and Its In Vitro Release
p.423

Ciprofloxacin-Releasing Bioabsorbable Polymer is Superior to Titanium in Preventing Staphylococcus Epidermidis Attachment and Biofilm Formation In Vitro
p.427

Indirect Cytotoxicity Evaluation of Silver Doped Bioglass Ag-S70C30 on Human Primary Keratinocytes
p.431

Antimicrobial Treatment of Dental Osseous Defects with Silver Doped Bioglass: Osteoblast Cell Response
p.435

Antimicrobiologic Property Hydrated Amorphous Calcium Phosphates Containing Silver
p.439

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Drug Loaded Porous Hydroxyapatite and Its In Vitro Release

Abstract:

Porous hydroxyapatite coated with mesoporous silica has been utilized as the matrix for controlled drug delivery. TEM observation confirms the pore size of mesoporous silica scatters about 50 Å. Porous hydroxyapatite was coated with mesoporous silica via sol-gel process. Ibuprofen and was loaded into the pores of mesoporous silica, and controlled release profiles were studied by soaking the samples in a simulated body fluid using a UV-VIS spectrophotometer.