The Influence of Geometrically Configured Sol-Gel Derived Hydroxyapatite Substrates on Osteoblast Response

Abstract:

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Good quality crystalline sol-derived Hydroxyapatite (HA) thin films of thickness ~350 nm on titanium substrates with underlying micro-channels were prepared by microwave annealing at a temperature of 400 °C for 30 min. A comprehensive in-vitro study was conducted to assess the osteoblast adhesive response to the well-defined micro-scale topographical features on HA coated and uncoated surfaces. The study confirmed the osteoblast’s response to the HA coated micro-channels with an elongated morphology. The effects to morphology suggest that osteoblast adhesion can be improved through optimal micro-channel design and may provide baseline design cues for improving the longterm performance of prosthetic orthopedic and dental implants.

Info:

Periodical:

Key Engineering Materials (Volumes 284-286)

Main Theme:

Edited by:

Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.

Pages:

569-572

DOI:

10.4028/www.scientific.net/KEM.284-286.569

Citation:

D. Adams et al., "The Influence of Geometrically Configured Sol-Gel Derived Hydroxyapatite Substrates on Osteoblast Response ", Key Engineering Materials, Vols. 284-286, pp. 569-572, 2005

Online since:

April 2005

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Price:

$35.00

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