Behavior of MC3T3-E1 Osteoblast-Like Cells Cultured on a Glass Substrate with Different Surface Roughness

Takao Saito; Hikoshiro Hayashi; K. Uoe; Takashi Kizuki; Kay Teraoka; Katsuya Kato; Yoshiyuki Yokogawa

doi:10.4028/www.scientific.net/KEM.284-286.573

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HomeKey Engineering MaterialsKey Engineering Materials Vols. 284-286Behavior of MC3T3-E1 Osteoblast-Like Cells...

Behavior of MC3T3-E1 Osteoblast-Like Cells Cultured on a Glass Substrate with Different Surface Roughness

Abstract:

Our experiments of mouse osteoblast-like MC3T3-E1 cells cultured on a glass substrate showed that as surface roughness of a substrate increased, cell proliferation, cell differentiation and subsequent mineralization were reduced.

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Periodical:

Key Engineering Materials (Volumes 284-286)

Pages:

573-576

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.284-286.573

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Online since:

April 2005

Authors:

Takao Saito, Hikoshiro Hayashi, K. Uoe, Takashi Kizuki, Kay Teraoka, Katsuya Kato, Yoshiyuki Yokogawa

Keywords:

Differentiation, Mineralization, Osteoblast, Proliferation, Surface Roughness (SR)

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References

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DOI: 10.1016/s0142-9612(02)00430-1

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