In Vitro Cytotoxicity Testing of Wood-Based Biomorphic SiC Ceramics

Alejandro de Carlos; Jacinto P. Borrajo; Julia Serra; Pio González; Sara Liste; Betty León

doi:10.4028/www.scientific.net/KEM.284-286.581

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HomeKey Engineering MaterialsKey Engineering Materials Vols. 284-286In Vitro Cytotoxicity Testing of Wood-Based...

In Vitro Cytotoxicity Testing of Wood-Based Biomorphic SiC Ceramics

Abstract:

The aim of this study was to test the in vitro cytotoxicity of wood-based biomorphic Silicon Carbide (SiC) ceramics, using MG-63 human osteoblast-like cells. This innovative material has been recently developed and it exhibits unique mechanical properties towards their application in biomedical technology. In the solvent extraction test the SiC ceramic extracts had almost no effect on cellular activity even at 100% concentration. A similar behaviour was found for Ti6Al4V and bioactive glass, used as reference materials. The results of the cell morphology and the cellular attachment response have also demonstrated that the in vitro performance of these biomorphic SiC ceramics is qualitatively comparable to that produced by titanium alloy and bioactive glass, which seems very promising.

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Periodical:

Key Engineering Materials (Volumes 284-286)

Pages:

581-584

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.284-286.581

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Online since:

April 2005

Authors:

Alejandro de Carlos, Jacinto P. Borrajo, Julia Serra, Pio González, Sara Liste, Betty León

Keywords:

Bioactive Glass, Bioceramic, MG-63 Cells, MTT Assay, Silicon Carbide (SiC), Ti₆Al₄V Alloy

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References

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