Adhesion, Proliferation and Morphology of Osteoblasts Cultured on Apatite Ceramics with Preferred Orientation to a-Plane

Akimitsu Miyazaki; Mamoru Aizawa

doi:10.4028/www.scientific.net/KEM.309-311.109

Paper Titles

Stability of Cultured Osteoblasts on Calcium Phosphate Ceramics
p.93

Novel Calcium Phosphate Ceramics: The Remarkable Promoting Action on the Differentiation of the Normal Human Osteoblasts
p.97

Sintering Effect on Mechanical Properties of Composites of Hydroxyapatite Lanthanum Oxide (HA-La₂O₃)
p.101

Osteoblast Proliferation and Morphology Analysis on Laser Modified Hydroxyapatite Surfaces: Preliminary Results
p.105

Adhesion, Proliferation and Morphology of Osteoblasts Cultured on Apatite Ceramics with Preferred Orientation to a-Plane
p.109

Rietveld Studies on Silicon Substituted Hydroxyapatite
p.113

Silicon Dissolution from Microporous Silicon Substituted Hydroxyapatite and its Effect on Osteoblast Behaviour
p.117

The Effect Orthosilicic Acid on Collagen Type I, Alkaline Phosphatase and Osteocalcin mRNA Expression in Human Bone-Derived Osteoblasts In Vitro
p.121

Preparation of Carbonate Apatite Monolith by Treatment of the Set Gypsum Containing Calcite in Trisodium Phosphate Solution
p.125

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Adhesion, Proliferation and Morphology of Osteoblasts Cultured on Apatite Ceramics with Preferred Orientation to a-Plane

Abstract:

There are two crystal planes in hydroxyapatite (Ca10(PO4)6(OH)2; HAp) that is clinically applied to artificial bone or dental root. The two crystal planes, a- and c-planes, are anisotropy. We have successfully fabricated dense HAp ceramics with preferred orientation to a-plane from single-crystal apatite fibers (AF) and apatite gels (AG). We examined the cellular response, such as adhesion, proliferation and morphology, of orthoclastic MC3T3-E1 cells, to the surface of the HAp ceramics with preferred orientation to a-plane. The initial cell attachment efficiency of the HAp ceramics with a-plane was lower than that of isotropic HAp ceramics as a control. This may be due to the difference of surface potential of the examined HAp ceramics. The proliferation of cells cultured on the HAp ceramics with a-plane was almost the same as that of isotropic HAp one.