Adhesion, Proliferation and Morphology of Osteoblasts Cultured on Apatite Ceramics with Preferred Orientation to a-Plane

Abstract:

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There are two crystal planes in hydroxyapatite (Ca10(PO4)6(OH)2; HAp) that is clinically applied to artificial bone or dental root. The two crystal planes, a- and c-planes, are anisotropy. We have successfully fabricated dense HAp ceramics with preferred orientation to a-plane from single-crystal apatite fibers (AF) and apatite gels (AG). We examined the cellular response, such as adhesion, proliferation and morphology, of orthoclastic MC3T3-E1 cells, to the surface of the HAp ceramics with preferred orientation to a-plane. The initial cell attachment efficiency of the HAp ceramics with a-plane was lower than that of isotropic HAp ceramics as a control. This may be due to the difference of surface potential of the examined HAp ceramics. The proliferation of cells cultured on the HAp ceramics with a-plane was almost the same as that of isotropic HAp one.

Info:

Periodical:

Key Engineering Materials (Volumes 309-311)

Main Theme:

Edited by:

Takashi Nakamura, Kimihiro Yamashita and Masashi Neo

Pages:

109-112

DOI:

10.4028/www.scientific.net/KEM.309-311.109

Citation:

A. Miyazaki and M. Aizawa, "Adhesion, Proliferation and Morphology of Osteoblasts Cultured on Apatite Ceramics with Preferred Orientation to a-Plane ", Key Engineering Materials, Vols. 309-311, pp. 109-112, 2006

Online since:

May 2006

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$35.00

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