Effect of Protein Addition on the Setting Behaviour of a Calcium Phosphate Cement

Abstract:

This study investigated the influence of the addition of various proteins to the liquid phase (albumin, fibrinogen and foetal bovine serum (FBS)) on the mechanical strength and setting time of a brushite forming calcium phosphate cement. Additions of 1wt% protein to the liquid phase led to a deterioration in compressive strength of the set cement by up to 50%. The setting time was not affected by adding albumin and FBS but was increased by 50% with admixtures containing fibrinogen. The conversion of the reactants, β-tricalcium phosphate and monocalcium phosphate, to brushite was found to be unaffected by addition of up to 10wt% proteins.

• Periodical: Key Engineering Materials (Volumes 309-311)
• Pages: 841-844
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.309-311.841
• Online since: May 2006
• Authors: S. Chauhan, M.P. Hofmann, R.M. Shelton
• Keywords: Bone Cement, Brushite, Mechanical Property, Protein Addition, Setting Time

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