Development and Characterization of β- Tricalcium Phosphate Cements Containing Chitosan
Cements were prepared by mixing the calcium phosphate (β-TCP) with phosphoric acid solution (2.6M) and chitosan solution (2.5% in acetic acid solution) that was added in different proportions, ranging from 1 to 50% of total acid solution amount. Observations using SEM showed that the used of chitosan increased the interconnectivity of grains in the final cement, although the mechanical resistance to compression decreased from approximately 3 to 1 MPa. Probably the chitosan macromolecule is able to form a more interconnected net.
Takashi Nakamura, Kimihiro Yamashita and Masashi Neo
M. S. Tonoli et al., "Development and Characterization of β- Tricalcium Phosphate Cements Containing Chitosan ", Key Engineering Materials, Vols. 309-311, pp. 845-848, 2006