Evaluation of Sodium Titanate Coating on Titanium by Sol-Gel Method In Vitro
In this study, an exclusive sodium titanate (Na2Ti6O13) coating on titanium was fabricated by sol-gel method and evaluated in vitro. The coating was characterized by SEM and XRD. The bioactivity of the Na2Ti6O13 coating was evaluated by the biomimetic growth of apatite on its surface after soaked in an acellular simulated body fluid (SBF) for a period of time. In vitro osteoblasts culture was carried out to determine cytocompatibility by the measurement of the proliferation and alkaline phosphatase (ALP) activity of the cells. XRD patterns showed that Na2Ti6O13 was well crystallized when the coating was heated at 800°C. SEM observation exhibited that the Na2Ti6O13 coated titanium had a homogeneous surface without any cracks. After immersion in SBF, the apatite layer can be formed on the coating. The cells culture showed that the osteoblasts grew well on the Na2Ti6O13 coated titanium. It can be concluded that Na2Ti6O13 coating on titanium obtained by sol-gel method is bioactive.
Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu
F. F. Wang et al., "Evaluation of Sodium Titanate Coating on Titanium by Sol-Gel Method In Vitro", Key Engineering Materials, Vols. 330-332, pp. 777-780, 2007