Insulin Adsorption by Hydroxyapatite

Abstract:

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In this study, the insulin adsorption ability by synthetic hydroxyapatite was investigated. Hydroxyapatite before thermal treatment and heated at 900°C and 1100°C were incubated in a solution containing 32 mg insulin/gHA. Adsorption and desorption experiments were carried out at 37°C under constant and slowly stirring. From FTIR results it was observed that insulin was tightly attached to HA surface after 96 hours adsorption experiment. Thermal pre-treatment on HA samples had no effect on insulin adsorption. However, protein desorption was more pronounced on samples not submitted to thermal treatment.

Info:

Periodical:

Key Engineering Materials (Volumes 396-398)

Main Theme:

Edited by:

Marcelo Prado and Cecília Zavaglia

Pages:

65-68

DOI:

10.4028/www.scientific.net/KEM.396-398.65

Citation:

E. Mavropoulos et al., "Insulin Adsorption by Hydroxyapatite", Key Engineering Materials, Vols. 396-398, pp. 65-68, 2009

Online since:

October 2008

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Price:

$35.00

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