Insulin Adsorption by Hydroxyapatite

Elena Mavropoulos; Nilce C.C.  da Rocha; Andrea Machado Costa; Maria Helena M. Rocha-Leão; Alexandre Mello; Antonella M. Rossi

doi:10.4028/www.scientific.net/KEM.396-398.65

Paper Titles

Adsorption of Proteins Derived from Fetal Bovine Serum onto Hydroxyapatite Nanocrystals with Quartz Crystal Microbalance Technique
p.47

Biocompatibility Properties of ZrO₂ Ceramics and ZrO₂-TiN Composites
p.51

Comparative Effect of the Ionic Products from Bioactive Glass Dissolution on the Behavior of Cementoblasts, Osteoblasts, and Fibroblasts
p.55

In Vivo Behavior of Hydroxyapatite Evaluated by Attenuated Total Reflection Infrared Microscopy (ATR-FTIR)
p.61

Insulin Adsorption by Hydroxyapatite
p.65

Performance Evaluation of Hydroxyapatite Coatings Thermally Sprayed on Surgical Fixation Pins
p.69

Protein Adsorption on Nanohydroxyapatites: Spectroscopic Investigations at Molecular Level
p.77

Resorption Mechanism of Hydroxyapatite and β-Tricalcium Phosphate Coating Layer
p.81

The Importance of Osteoclast-Like Multinucleated Cells in Material-Induced Osteoinduction: A Comparative Study between Dogs and Rats
p.85

HomeKey Engineering MaterialsKey Engineering Materials Vols. 396-398Insulin Adsorption by Hydroxyapatite

Insulin Adsorption by Hydroxyapatite

Abstract:

In this study, the insulin adsorption ability by synthetic hydroxyapatite was investigated. Hydroxyapatite before thermal treatment and heated at 900°C and 1100°C were incubated in a solution containing 32 mg insulin/gHA. Adsorption and desorption experiments were carried out at 37°C under constant and slowly stirring. From FTIR results it was observed that insulin was tightly attached to HA surface after 96 hours adsorption experiment. Thermal pre-treatment on HA samples had no effect on insulin adsorption. However, protein desorption was more pronounced on samples not submitted to thermal treatment.

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Periodical:

Key Engineering Materials (Volumes 396-398)

Pages:

65-68

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.396-398.65

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Online since:

October 2008

Authors:

Elena Mavropoulos, Nilce C.C. da Rocha, Andrea Machado Costa, Maria Helena M. Rocha-Leão, Alexandre Mello, Antonella M. Rossi

Keywords:

Bone, FT-IR, Hydroxyapatite (HAP), Insulin

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