Silver-Doped Apatite as a Bioactive and an Antimicrobial Bone Material
Phase-pure nanostructured silver-doped hydroxyapatite (nAgHA) of various Ag contents was synthesised. These nAgHA were then evaluated in-vitro using human mesenchymal stem cells (hMSCs) and Escherichia coli (E. coli). Results revealed that hMSCs grew generally well on all nAgHA at all time points. In addition, fewer E. coli were seen attaching on the surface of all nAgHA. Hence, this work demonstrated that nAgHA offers considerable potential as a biomaterial.
Eyup Sabri Kayali, Gultekin Goller and Ipek Akin
E. S. Thian et al., "Silver-Doped Apatite as a Bioactive and an Antimicrobial Bone Material", Key Engineering Materials, Vols. 493-494, pp. 27-30, 2012