Fabrication of Organic/Inorganic Hybrids by Infiltration of Commercially-Available PLGA into Porous Hydroxyapatite Ceramics and its Material Properties

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Hybrids of hydroxyapatite (HAp) and poly(L-lactic co glycolic) (PLGA) have been fabricated, which can be expected to be a novel filler for bone grafting. The porous HAp ceramics with bimodal pore structure have been fabricated from apatite fibers synthesized by homogeneous precipitation method. Then, HAp/PLGA hybrids have been fabricated by introducing PLGA having high molecular-weight into the open pores of the porous HAp ceramics. Total porosities of the porous HAp ceramics slightly decreased from 71.5% down to 67.4% after infiltrating PLGA into the porous HAp ceramics. The bending strength of the HAp/PLGA hybrids was ~ 8.3 MPa. The value attained about 2 times that of the porous HAp ceramics.

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Periodical:

Key Engineering Materials (Volumes 493-494)

Main Theme:

Edited by:

Eyup Sabri Kayali, Gültekin Göller and Ipek Akin

Pages:

556-560

Citation:

N. Osada et al., "Fabrication of Organic/Inorganic Hybrids by Infiltration of Commercially-Available PLGA into Porous Hydroxyapatite Ceramics and its Material Properties", Key Engineering Materials, Vols. 493-494, pp. 556-560, 2012

Online since:

October 2011

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$41.00

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