Fabrication of Organic/Inorganic Hybrids by Infiltration of Commercially-Available PLGA into Porous Hydroxyapatite Ceramics and its Material Properties

Naoki Osada; Yusuke Shigemitsu; Masashi Makita; Kazuya Oribe; Mamoru Aizawa

doi:10.4028/www.scientific.net/KEM.493-494.556

Paper Titles

Characterization of Plasma Sprayed Yittria Stabilized Zirconia (8 wt %) Hydroxyapatite Coatings
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Pore Morphology in MAO Produced Oxide Film Modified by Magnesium Integration
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Fabrication of Bioactive Apatite Nuclei-Precipitated Composites
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Comparison of Microstructures of Bovine Hydroxyapatite and Sol-Gel Derived Porous Alumina-Hydroxyapatite Biocomposite Powders
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Fabrication of Organic/Inorganic Hybrids by Infiltration of Commercially-Available PLGA into Porous Hydroxyapatite Ceramics and its Material Properties
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Silicate and Calcium Ions Releasing Biomaterials for Bone Reconstruction
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Production and Characterization of Bioglass^®-Titania Reinforced Hydroxylapatite Composite
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Preparation and Characterization of Polylactide-co-glycolide/Carbonate Apatite (PLGA/CHA) Composite Scaffolds
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Gradient Organic Inorganic Nanocomposites for Tissue Repair at the Cartilage/Bone Interface
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HomeKey Engineering MaterialsKey Engineering Materials Vols. 493-494Fabrication of Organic/Inorganic Hybrids by...

Fabrication of Organic/Inorganic Hybrids by Infiltration of Commercially-Available PLGA into Porous Hydroxyapatite Ceramics and its Material Properties

Abstract:

Hybrids of hydroxyapatite (HAp) and poly(L-lactic co glycolic) (PLGA) have been fabricated, which can be expected to be a novel ﬁller for bone grafting. The porous HAp ceramics with bimodal pore structure have been fabricated from apatite fibers synthesized by homogeneous precipitation method. Then, HAp/PLGA hybrids have been fabricated by introducing PLGA having high molecular-weight into the open pores of the porous HAp ceramics. Total porosities of the porous HAp ceramics slightly decreased from 71.5% down to 67.4% after infiltrating PLGA into the porous HAp ceramics. The bending strength of the HAp/PLGA hybrids was ~ 8.3 MPa. The value attained about 2 times that of the porous HAp ceramics.

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Key Engineering Materials (Volumes 493-494)

Pages:

556-560

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.493-494.556

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Online since:

October 2011

Authors:

Naoki Osada, Yusuke Shigemitsu, Masashi Makita, Kazuya Oribe, Mamoru Aizawa

Keywords:

Hydroxyapatite (HAP), Inorganic Hybrid, Organic Hybrid, PLGA, Porous Ceramics

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References

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