CMOS Amplifier for Neural Signal Recording Applications

Zhang Zhang; Zheng Xi Cheng; Yi Wei Zhuang

doi:10.4028/www.scientific.net/KEM.645-646.1279

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HomeKey Engineering MaterialsKey Engineering Materials Vols. 645-646CMOS Amplifier for Neural Signal Recording...

CMOS Amplifier for Neural Signal Recording Applications

Abstract:

A low power low noise CMOS amplifier with integrated filter for neural signal recording is designed and fabricated with CSMC 0.5 μm CMOS process. DC offsets introduced by electrode-tissue interface are rejected through a feedback low-pass filter. The bandwidth of the amplifier is in 3.5Hz-5.5KHz range, and the gain is about 48dB in the midband. AC input differential mode voltage range is 10mV, and DC input differential mode voltage range is 180mV. The amplifier can accommodate 180mV DC offsets drift and 10mV neural spikes. The neural probe array is integrated directly on the surface of the amplifier array chip, and is tested in saline solution, and also is implanted in rats in vivo , the results of the experiments show that the amplifier is suitable for neural signal recording. The power dissipation is about 14μW while consuming 0.16 mm² of chip area, which satisfies implantable devices requirements.

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Periodical:

Key Engineering Materials (Volumes 645-646)

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1279-1284

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.645-646.1279

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Online since:

May 2015

Authors:

Zhang Zhang, Zheng Xi Cheng*, Yi Wei Zhuang

Keywords:

CMOS Amplifier, Neural Probe, Neural Signal

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* - Corresponding Author

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