For Libraries For Publication Open Access Downloads About Us Contact Us
Paper Titles
In Vivo Evaluation of Strontium-Containing Nanostructured Carbonated Hydroxyapatite
p.212
In Vivo Evaluation of Zinc-Containing Nanostructured Carbonated Hydroxyapatite
p.223
Studies on Connexin 43, a Gap-Junction Protein, in P19 Embryonal Carcinoma Cells after Culture on an Apatite Fiber Scaffold
p.230
Cytocompatiblity of Ceramic Nanoparticles to Various Types of Cells
p.234
Hollow Shells Development and Characterization for Cells Carrying Purpose
p.238
Bioceramic Drug Delivery System for Cancer Treatment and Regenerative Medicine
p.245
Preparation of Carbonated Apatite Membrane as Metronidazole Delivery System for Periodontal Application
p.250
Enzyme Immobilization by Using Apatite Microcapsules with Magnetic Properties
p.259
Interface Function and Cefazolin-Adsorption-Release Characteristics of Hydroxyapatite Granules Modified by Supersonic Treatment Techniques
p.265

Hollow Shells Development and Characterization for Cells Carrying Purpose

Article Preview

Abstract:

Bioceramics draw attention in bone tissue engineering field since their biomimetic properties regarding bone attribute. In this context, a concept of smart bioceramics granules made of Hydroxyapatite have been set up, enhancing surface area available to body fluids containing proteins and cell adhesion for bone forming respectively thanks to microporosities and macropore concavities. New “hollow shell” granules were developed and assessed by physico-chemical characterizations, in-vitro experiments and in-vivo implantation in comparison with classical round granules. This new original galenic formulation showed promising potential in cell carrying and osteoconduction matter.

You might also be interested in these eBooks
Bioceramics 27 View Preview

Info:

Periodical:

Key Engineering Materials (Volume 696)

Pages:

238-242

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.696.238

Citation:

Cite this paper

Online since:

May 2016

Authors:

Thomas Miramond*, Pascal Borget, Françoise Moreau, Borhane Fellah, Guy Daculsi

Keywords:

Biomaterials, Calcium Phosphate, Hollow Granule, Osteoconduction

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

© 2016 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

* - Corresponding Author

References

[1] Christopher G (2002) Bone-grafting and bone-graft substitutes. J Bone Joint Surg 84: 454-464.

DOI: 10.2106/00004623-200203000-00020

Google Scholar

[2] Moore WR, Graves SE, Bain GI (2001) Synthetic bone graft substitutes. ANZ journal of surgery 71: 354-361.

DOI: 10.1046/j.1440-1622.2001.02128.x

Google Scholar

[3] Dorozhkin SV (2002) A review on the dissolution models of calcium apatites. Progress in Crystal Growth and Characterization of Materials 44: 45-61.

DOI: 10.1016/s0960-8974(02)00004-9

Google Scholar

[4] LeGeros RZ (2002) Properties of osteoconductive biomaterials: calcium phosphates. Clinical Orthopaedics and Related Research 395: 81.

DOI: 10.1097/00003086-200202000-00009

Google Scholar

[5] LeGeros R, Lin S, Rohanizadeh R, Mijares D, Legeros J, (2003) Biphasic calcium phosphate bioceramics: preparation, properties and applications. Journal of Materials Science: Materials in Medicine 14: 201-209.

DOI: 10.4028/www.scientific.net/kem.240-242.473

Google Scholar

[6] Bohner M (2000) Calcium orthophosphates in medicine: from ceramics to calcium phosphate cements: Injury 31: D37-D47.

DOI: 10.1016/s0020-1383(00)80022-4

Google Scholar

[7] Gauthier O, Bouler JM, Aguado E, Pilet P, Daculsi G (1998) Macroporous biphasic calcium phosphate ceramics: influence of macropore diameter and macroporosity percentage on bone ingrowth. Biomaterials 19: 133-139.

DOI: 10.1016/s0142-9612(97)00180-4

Google Scholar

[8] Ripamonti U, Roden L (2010) Biomimetics for the induction of bone formation. Expert review of medical devices 7: 469-479.

DOI: 10.1586/erd.10.17

Google Scholar

[9] Habibovic P, Yuan H, Van Der Valk CM, Gert Meijer, Clemens A van Blitterswijk, Klass de Groot (2005) 3D microenvironment as essential element for osteoinduction by biomaterials. Biomaterials 26: 3565-3575.

DOI: 10.1016/j.biomaterials.2004.09.056

Google Scholar

[10] Malard O, Gautier H, Daculsi G (2007) In Vivo Demonstration of 2 Types of Microporosity on the Kinetic of Bone Ingrowth and Biphasic Calcium Phosphate Bioceramics Resorption Key Engineering Materials 361-363: 1233-1236.

DOI: 10.4028/www.scientific.net/kem.361-363.1233

Google Scholar

[11] Bohner M, Baumgart F (2004) Theoretical model to determine the effects of geometrical factors on the resorption of calcium phosphate bone substitutes. Biomaterials 25: 3569-3582.

DOI: 10.1016/j.biomaterials.2003.10.032

Google Scholar

[12] Daculsi G, Layrolle P (2004) Osteoinductive Properties of Micro Macroporous Biphasic Calcium Phosphate Bioceramics. Key Engineering Materials 254-256: 1005-1008.

DOI: 10.4028/www.scientific.net/kem.254-256.1005

Google Scholar

[13] Ripamonti U (1996) Osteoinduction in porous hydroxyapatite implanted in heterotopic sites of different animal models. Biomaterials 17: 31-35.

DOI: 10.1016/0142-9612(96)80752-6

Google Scholar

[14] Plank C, Eglin D, Fahy N, Sapet C, Borget P, van Osch G, Gentili C, Miramond T, Zöller K, Anton M (2012) Gene activated matrices for bone and cartilage regeneration in arthritis. European Journal of Nanomedicine 4: 17-32.

DOI: 10.1515/ejnm-2012-0001

Google Scholar

[15] Daculsi G (2015), Smart Scaffolds: the Future of Bioceramic, J Mater Sci: Mater Med (2015) 26: 154.

DOI: 10.1007/s10856-015-5482-7

Google Scholar

© 2025 Trans Tech Publications Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For open access content, terms of the Creative Commons licensing CC-BY are applied.
Scientific.Net is a registered trademark of Trans Tech Publications Ltd.