RF-Magnetron Sputtered Silica Interlayer on β-TCP Granules for Mesoporous Silica Coating

Yoshiyuki Yokogawa; Atsumasa Shishido; Y. Shigarami

doi:10.4028/www.scientific.net/KEM.782.207

Paper Titles

Changes in Surface Condition during Fabrication Process of Bioactive Apatite Nuclei Incorporated PEEK
p.182

Wettability and Durability of Si-O Coatings on Zirconia Substrate by RF-Magnetron Plasma Sputtering
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Adhesion and Scratch Testing of Antibiotic Loaded Poly-Lactic Acid Biocomposite Thin Films on Metallic Implants
p.195

Preparation of Calcium Phosphate Coated Simvastatin-Loaded PLGA Microspheres Dispersed Alginate Hydrogel Beads as a Controlled Drug Delivery Carrier
p.201

RF-Magnetron Sputtered Silica Interlayer on β-TCP Granules for Mesoporous Silica Coating
p.207

Multifunctional-Dual Drug Delivery Poly-Lactic Acid Biocomposite Coating with Hydroxyapatite for Bone Implants
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MC3T3-E1 Cellular Response and Protein Detection on Surface Potential-Controlled TiO₂ Scale in Serum-Containing Medium
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Sintering Temperature Effect on Hardness of Self-Synthetisized Porcelain Made from Natural Sumatran Sand without Kaolin
p.227

Loading of Fluvastatin onto Gelatin-Coated Titanium Implants
p.233

HomeKey Engineering MaterialsKey Engineering Materials Vol. 782RF-Magnetron Sputtered Silica Interlayer on β-TCP...

RF-Magnetron Sputtered Silica Interlayer on β-TCP Granules for Mesoporous Silica Coating

Abstract:

Mesoporous silica (MPS) coatings on β-tricalcium phosphate (β-TCP) granules and their protein adsorptive capabilities were studied. β-TCP granules containing 2 wt% of aluminum oxide and 6 wt% of silicon oxide were prepared using a pan-type granulator and heated at 1200 oC. MPS coatings on β-TCP granules was carried out by a dip-coating method, but the β-TCP granules were not covered by the MPS particles. A silica interlayer was formed on the β-TCP granules via magnetron sputtering prior to the coating of the MPS. The β-TCP granules coated with the silica interlayer were fully covered by the MPS particles. A silica interlayer may offer bonding between the β-TCP granules and MPS coating. The adsorption of protein on the MPS-coated β-TCP granules was evaluated by UV-VIS spectroscopy. The adsorption capacity of protein on the β-TCP granules was improved by the MPS coatings on the β-TCP granules, and that of the β-TCP granules coated with the silica interlayer showed a higher protein adsorption capacity.