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Effect of Nano Biphasic Calcium Phosphate Bioceramics on Periodontal Regeneration in the Treatment of Alveolar Defects

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Abstract:

The aim of the present study is to investigate the efficacy of nanobiphasic calcium phosphate (nanoBCP) bioceramic in the treatment of periodontal osseous defects. Alveolar bone defects were surgically created bilaterally at the buccal aspects of four second premolars in two beagle dogs. After root leveling, nanoBCP was randomly filled in one defect and nothing was put into the contralateral defect as negative controls. Bioglass was randomly filled in one of left defect as positive controls and nothing was put into the contralateral defect as negative controls. Dogs were killed at the 12th week. Histological observations were processed through a light microscopy. The results reveal that a great amount of functional periodontal fissures formed in the defects in the nanoBCP groups and bioglass groups while no new bone formed in the control groups at all. In this study, nanoBCP has proven to work well as a biocompatible and bioactive material to promote periodontal regeneration effectively.

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Periodical:

Advanced Materials Research (Volume 486)

Pages:

422-425

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.486.422

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Online since:

March 2012

Authors:

Lan Lei Wang, Ji Hua Li, Yong Tao Xie, Pi Shan Yang, Yun Mao Liao, Gong Ling Guo

Keywords:

Alveolar Bone, Bioglass, Bone Graft, Nano Biphasic Calcium Phosphate

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© 2012 Trans Tech Publications Ltd. All Rights Reserved

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