Applied Mechanics and Materials Vols. 411-414

Abstract: The alkaloid is one of the most important components in Chinese traditional medicine plants. It is of great significance for studying of alkaloids material about how to extract the alkaloids from the Chinese native medicine ingredient effectively due to the extremely important pharmacological activities of it. The traditional methods and the progress of the application of new technology of preparations of alkaloid were reviewed in the paper. At present, traditional extraction include water and acid water extraction, alcohol solvent extraction, lipophilic organic solvent extraction, new technologies such as UAE, MAE, enzymatic, SBE and hyphenated techniques. Then the development prospect of preparations of alkaloids was discussed by analyzing the principle and advantages and disadvantages of them.

Abstract: The present paper reviews the research on the medicinal value of Amaryllidaceae plants. The medicinal value of Amaryllidaceae plants attracts much attention nowadays by By discovery the pharmaco-activity of alkaloid series within plants etc. Lycoris radiata, Crinum asiaticum L. Kafir Lily, Curculigo orchioides gaertn. This paper mainly discourses the mecicinal value on the pharmaco-activity of Amaryllidaceae plants. The study found that Amaryllidaceae plants have effects on anti-tumor, antiinflammatory, antibiosis, and antiviral, antimalarial and so on, and have some effects on the immune system, central nervous system, inhibition AcCHE.

Abstract: Classifiers based on discriminant model achieved the highest accuracy compared to other protein classification methods in remote homology detection, but all of the classifiers were troubled by imbalance training in modeling. This paper presented a protein classification based on optimization of discriminant model to further improve the classifier performance by setting different penalty coefficients for the positive and negative samples to balance the training set weights. Comparative experiments show that the method based on optimized discriminant model obtained higher accuracy, and the method can improve the performance of all classifiers based on discriminant model by optimization of the parameters.

Abstract: Since it was found that Zymosan had activity of anti-tumor at 1960s, polysaccharides have attracted more and more researchers’ attentions in the field of anti-tumor. In recent years, researches on polysaccharides get many outstanding achievements in anti-tumor field. Polysaccharides from plants have been proved that their activity of anti-tumor is related to their molecular structures very closely. The critical factors that influence bioactivities of polysaccharides are as follows: polysaccharide’s molecular weight, saccharide unit of polysaccharide’s main-chain, configuration of glycosidic bond, degree of branch, spatial structure, and functional group modification, etc. We analyze and summarize structural modification and structure-activity relationship about anti-tumor of polysaccharides from plants in this article, based on our study and associated with other researches’ progress in the world.

Abstract: The researches on plant polysaccharides develop rapidly in recent years. In this paper, the studies of pharmaceutical chemistry of polysaccharides from plants are reviewed. We introduce researches’ new progresses and results of the extraction, separation and purification in the field of pharmaceutical chemistry and expound the advantages and disadvantages of the applications of physical techniques, chemical technology and biotechnology. The applications of statistic principles in the field of medicinal chemistry are also discussed in this article.

Abstract: The development of tumor is not only results of the uncontrolled cell proliferation, the differentiation and cell abnormalities, but also relates to apoptosis imbalance. Inducing tumor cell apoptosis has become an important means of clinical applications on cancer treatment. Apoptosis of tumor cells is affected by a variety of gene regulation, including some oncogenes and tumor suppressor genes which are related to cell proliferation. Focusing on the three basic ways of apoptosis: death receptor pathway, the mitochondrial pathway, and endoplasmic reticulum stress pathway, This paper summarizes the research progress of appoptosis factors for the past few years and provides information and ideas for finding out effective anticancer drugs which have key anti-cancer factors as target points.

Abstract: With the rising incidence of cancer, the research of natural medicine anti-cancer becomes a hot spot. This article used several typical activities compounds from plants such as Taxaceae, Davidia involucrata branch, Lily section, Fabaceae, Labiatae, oleander branch, Zingiberaceae, and Celastraceae, and then analyzed the activity of different types of cancer anticancer.

Abstract: The flavonoids are the active ingredient of many natural medicines, it can inhibit the proliferation of many kinds of tumor cells. In recent years, a growing number of studies have shown that through various mechanisms of flavonoids inhibit the angiogenesis and tumor growth. The article reviews the research advances of the anti-tumor angiogenesis of flavonoids.

Abstract: The fully controlled crop cultivation system suggested in this study is intended to develop the cultivation model for stable production of medicinal crops under enclosed environment not affected by natural settings. In this paper, the features of the fully controlled crop cultivation system for detecting optimum conditions of medicinal crop cultivation are explored and technical components to be considered upon developing the system are reviewed.

Abstract: With the development of modern industry, the problem of environment pollution becomes more and more serious. It has become an important issue to conduct the environment monitoring rapidly and effective. Fish, alga, higher aquatic plants and benthic macro-invertebrate are always used in the environment monitoring. In recent years, protozoa are widely applied to the monitor of soil environment pollution and water pollution. Protozoa are the most original and the lowest unicellular animals, and they play an important role as the predator and primary consumer in the energy flow and circulation of materials. Protozoa become an ideal model animal in the process of assessing the quality change.