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Temperature-Sensitive Nanogels PNIPAAm/DMA Prepared and Research

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Abstract:

There have much study about thermo-responsive nanogels,which exhibit temperature-controlled volume phase transitions.There have been few reports,however,of electrostatically neutral,thermosensitive nanogels with a high composition of hydrophilic monomer.Here,we describe the synthesis and characterization of a new class of nonionic copolymer nanogels based on N-ispropylacrylamide(NIPAM) and N,N-dimethylacrylamide(DMA),wich exhibit tunable volume phase transition temperatures.And increasing percentages of DMA in copolymer gels raises the LCST,and attenuates and broadens the volume phases transition.Through DLS, AFM and UV-Vis measurement it's size,shape and VPTTs.The character of nonionic NIPAM/DMA nanogels show it's tunable phase transitions promise to be useful for applicatipns in biotechnology and medicine.

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Periodical:

Advanced Materials Research (Volume 465)

Pages:

141-145

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.465.141

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Online since:

February 2012

Authors:

Hai Yan Wang, Qian Liao, Qiao Lan Shao, Gao Qiu, Xi Hua Lu

Keywords:

N,N-Dimethylacrylamide, N-Ispropylacrylamide, Temperature-Sensitive Hydrogels

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© 2012 Trans Tech Publications Ltd. All Rights Reserved

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