Assessing the Effect of Nano Biphasic Calcium Phosphate on Acute Alveolar Bone Defects in Beagle Dogs Using Micro-Computed Tomography Imaging

Lan Lei Wang; He Ying Hou; Jian Xin Zhang; Zong Mei Sun; Pi Shan Yang; Yun Mao Liao

doi:10.4028/www.scientific.net/AMR.465.132

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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 465Assessing the Effect of Nano Biphasic Calcium...

Assessing the Effect of Nano Biphasic Calcium Phosphate on Acute Alveolar Bone Defects in Beagle Dogs Using Micro-Computed Tomography Imaging

Abstract:

The aim of the present study was to assess the effect of nano-biphasic calcium phosphate (nanoBCP) scaffolds on acute alveolar bone defects in beagle dogs by micro-computed tomographic imaging (μCT). Alveolar bone defects were surgically created bilaterally at the buccal aspects of the upper second premolars in four beagle dogs. After root conditioning with ethylenediaminetetraacetate (EDTA), nanoBCP was randomly filled in the defects and nothing was put into the contralateral defects as controls. Dogs were killed at the 24th weeks. Specimens were scanned and reconstructed though μCT. The results revealed that much new alveolar bone formed in the defects in the nanoBCP groups while no new alveolar bone formed in the controls. The present results indicate that PBCP may enhance alveolar bone regeneration in acute-type labial dehiscence defects.

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Periodical:

Advanced Materials Research (Volume 465)

Pages:

132-135

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.465.132

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Online since:

February 2012

Authors:

Lan Lei Wang, He Ying Hou, Jian Xin Zhang, Zong Mei Sun, Pi Shan Yang, Yun Mao Liao

Keywords:

Alveolar Bone, Bone Graft, Nano Biphasic Calcium Phosphate

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