Optimized Extraction of Ganglioside from Sika Deer Antler

Article Preview

Abstract:

In this study the extraction of ganglioside from the lipid soluble fraction of sika deer antler was investigated using response surface methodology (RSM). A three-level Box-Behnken design which was based on the results of a single-factor test was employed to optimize the parameters for extraction of ganglioside. The experimental results were fitted with a second-order polynomial equation by a multiple regression analysis. By solving the regression equation and also by analyzing the response surface contour plots, the optimal ganglioside extraction conditions were determined: ratio of liquid to raw material 11, temperature 40°C and time 7min, and the maximum yield of ganglioside extraction was 1.25%.

You might also be interested in these eBooks

Info:

Periodical:

Advanced Materials Research (Volumes 850-851)

Pages:

1133-1136

Citation:

Online since:

December 2013

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2014 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

* - Corresponding Author

[1] R. Zhou and S. H. Li: Journal of Food Composition and Analysis, Vol. 22 (2009), p.72.

Google Scholar

[2] R. Zhou, S. H. Li and D. C. Zhang: Chinese Journal of Chemical Engineering, Vol. 17 (2009) No. 3, p.373.

Google Scholar

[3] R. Zhou and S. H. Li: Food Chemistry, Vol. 114 (2009), p.1321.

Google Scholar

[4] R. Zhou, J. Y. Wang, S. F. Li and Y. Liu: Separation and Purification Technology, Vol. 65 (2009), p.275.

Google Scholar

[5] X.G. Chen, D.Y. Chang, Z.Y. Cui and B.X. Wang: Pharmacology and Clinics of Chinese Materia Medica, Vol. 8 (1992), p.17.

Google Scholar

[6] Y.Z. Zhang, G.L. Liu, X. G Chen and S.G. Bai: Journal of Gerontology, Vol. 12 (1992), p.165.

Google Scholar

[7] B.X. Wang, X.H. Zhao, X.W. Yang, S. Kaneko, M. Hattori, T. Namba and Y. Nomura: Journal of Medical and Pharmaceutical Society for WAKAN-YAKU, Vol. 5 (1988), p.123.

Google Scholar

[8] G.Y. Qiu, D.D. Huang, Y.F. Deng, Y. Wu, H.N. Huang and M.Z. Cui: Chinese medicine guide, Vol. 1 (2013) No. 11, p.532.

Google Scholar

[9] J. S. Schneider, S. M. Gollomp, S. Sendek, A. Colcher, F. Cambi and W. Du: Journal of the Neurological Sciences Vol. 1-2(2013) No. 324, p.140.

DOI: 10.1016/j.jns.2012.10.024

Google Scholar